Evidence map›Paper›PMID 39519253›Full record

ArticleInternational journal of molecular sciences2024

Serum Lipoprotein Profiling by NMR Spectroscopy Reveals Alterations in HDL-1 and HDL-2 Apo-A2 Subfractions in Alzheimer's Disease.

Jonas Ellegaard Mortensen, Trygve Andreassen, Dorte Aalund Olsen, Karsten Vestergaard, Jonna Skov Madsen, Søren Risom Kristensen, Shona Pedersen

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonas Ellegaard MortensenDepartment of Clinical Biochemistry, Aalborg University Hospital, 9000 Aalborg, Denmark.
Trygve AndreassenDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, 7491 Trondheim, Norway.ORCID 0000-0001-5295-5501
Dorte Aalund OlsenDepartment of Biochemistry and Immunology, Lillebaelt Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0003-2589-738X
Karsten VestergaardDepartment of Neurology, Aalborg University Hospital, 9000 Aalborg, Denmark.ORCID 0009-0008-6301-772X
Jonna Skov MadsenDepartment of Biochemistry and Immunology, Lillebaelt Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0001-6668-4714
Søren Risom KristensenDepartment of Clinical Biochemistry, Aalborg University Hospital, 9000 Aalborg, Denmark.ORCID 0000-0002-2649-506X
Shona PedersenDepartment of Basic Medical Science, College of Medicine, Qatar University, QU Health, Doha 2713, Qatar.ORCID 0000-0001-6636-0293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying biomarkers for Alzheimer's disease (AD) is crucial, due to its complex pathology, which involves dysfunction in lipid transport, contributing to neuroinflammation, synaptic loss, and impaired amyloid-β clearance. Nuclear magnetic resonance (NMR) is able to quantify and stratify lipoproteins. The study investigated lipoproteins in blood from AD patients, aiming to evaluate their diagnostic potential. Serum and plasma were collected from AD patients (

Indexed as

Alzheimer DiseaseBiomarkersMagnetic Resonance SpectroscopyAgedAged, 80 and overApolipoprotein A-IIFemaleHumansLipoproteins, HDLLipoproteins, HDL2MaleMiddle AgedApolipoprotein A-IIBiomarkersLipoproteins, HDLLipoproteins, HDL2Alzheimer’s diseasebiomarkerbloodlipoproteinsnuclear magnetic resonanceserum

Identifiers

PMID39519253
PMCPMC11546761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.