Evidence map›Paper›PMID 39519120›Full record

Trial reportInternational journal of molecular sciences2024

Weight Changes Are Linked to Adipose Tissue Genes in Overweight Women with Polycystic Ovary Syndrome.

Anton Hellberg, Daniel Salamon, Dorina Ujvari, Mikael Rydén, Angelica Lindén Hirschberg

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anton HellbergDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0001-6274-8354
Daniel SalamonDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Dorina UjvariDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Mikael RydénDepartment of Medicine Huddinge (H7), Karolinska Institutet, C2-94 Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden.
Angelica Lindén HirschbergDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.

Funding

Karolinska Institutet ALHStockholm County Council ALH 2016-0349Stockholm County Council ALH 2021-0855The Swedish Research Council ALH 2017-02051The Swedish Research Council ALH 2021-01378
6 · The paper itself

Abstract

Women with polycystic ovary syndrome (PCOS) have varying difficulties in achieving weight loss by lifestyle intervention, which may depend on adipose tissue metabolism. The objective was to study baseline subcutaneous adipose tissue gene expression as a prediction of weight loss by lifestyle intervention in obese/overweight women with PCOS. This is a secondary analysis of a randomized controlled trial where women with PCOS, aged 18-40 and body mass index (BMI) ≥ 27 were initially randomized to either a 4-month behavioral modification program or minimal intervention according to standard care. Baseline subcutaneous adipose tissue gene expression was related to weight change after the lifestyle intervention. A total of 55 obese/overweight women provided subcutaneous adipose samples at study entry. Weight loss was significant after behavioral modification (-2.2%,

Indexed as

OverweightPolycystic Ovary SyndromeWeight LossAdipose TissueAdolescentAdultBody Mass IndexFemaleHumansObesitySubcutaneous FatYoung Adultadipose tissuegene expressionlifestyleobesityPCOSweight loss

Identifiers

PMID39519120
PMCPMC11547111

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.