Evidence map›Paper›PMID 39519054›Full record

ReviewInternational journal of molecular sciences2024

The Variability of the Salivary Antimicrobial Peptide Profile: Impact of Lifestyle.

Mariana Gallo, Elena Ferrari, Laura Giovati, Thelma A Pertinhez, Lorenza Artesani, Stefania Conti, Tecla Ciociola

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. [Age-Related Changes in the Oral Microbiota].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Saliva-driven surface-engineeredBioactive materials · 2026
    Article
  7. Article
  8. Role of Innate Oral Immunity and the Salivary Fluid in Inflammatory Bowel Disease.Cellular and molecular gastroenterology and hepatology · 2026
    Article
  9. From gut to mouth: salivary signatures of carcinogenic microbiota.Frontiers in cellular and infection microbiology · 2026
    Review
  10. Compatibility of toothpastes with probiotics for periodontal health: anFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariana GalloLaboratory of Biochemistry and Metabolomics, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.ORCID 0000-0002-0022-4499
Elena FerrariLaboratory of Biochemistry and Metabolomics, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Laura GiovatiLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-7514-1789
Thelma A PertinhezLaboratory of Biochemistry and Metabolomics, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.ORCID 0000-0002-3065-6567
Lorenza ArtesaniLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-8765-8654
Stefania ContiLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-9973-8352
Tecla CiociolaLaboratory of Microbiology and Virology, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-6499-2545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saliva is crucial in maintaining oral health; its composition reflects the body's physiological and diseased state. Among salivary components, antimicrobial peptides (AMPs) stand out for their broad antimicrobial activities and role in modulating the oral microbiota and innate immune response. Local and systemic diseases can affect the levels of AMPs in saliva, making them attractive biomarkers. However, the large variability in their concentrations hampers their use in diagnostics. Knowledge of the various factors influencing the profile of salivary AMPs is essential for their use as biomarkers. Here, we examine how lifestyle factors such as physical activity, dietary supplementation, tobacco smoking, and psychological stress impact salivary AMP levels. By understanding these sources of variability, we can take a step forward in using AMPs for diagnostics and prognostics and develop new tailored and preventative approaches.

Indexed as

Antimicrobial PeptidesLife StyleSalivaBiomarkersExerciseHumansImmunity, InnateStress, PsychologicalAntimicrobial PeptidesBiomarkersantimicrobial peptides’ profilesbiomarkerslifestylesalivavariability

Identifiers

PMID39519054
PMCPMC11547034

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.