Evidence map›Paper›PMID 39518979›Full record

ReviewInternational journal of molecular sciences2024

Use of Hydrogels in Regenerative Medicine: Focus on Mechanical Properties.

Flavia Carton, Manuela Rizzi, Elena Canciani, Gianluca Sieve, Dalila Di Francesco, Simona Casarella, Luca Di Nunno, Francesca Boccafoschi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  15. Article
  16. An Evaluation of Cellulose Hydrogels Derived fromGels (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Flavia CartonDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0001-6310-9079
Manuela RizziDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-6174-7111
Elena CancianiDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-6987-6794
Gianluca SieveDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.
Dalila Di FrancescoDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0009-0003-4208-9672
Simona CasarellaDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.
Luca Di NunnoDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.
Francesca BoccafoschiDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-6734-5447

Funding

NODES project - MUR - M4C2 1.5 of PNRR ECS0000003
6 · The paper itself

Abstract

Bioengineered materials represent an innovative option to support the regenerative processes of damaged tissues, with the final objective of creating a functional environment closely mimicking the native tissue. Among the different available biomaterials, hydrogels represent the solution of choice for tissue regeneration, thanks to the easy synthesis process and the highly tunable physical and mechanical properties. Moreover, hydrogels are biocompatible and biodegradable, able to integrate in biological environments and to support cellular interactions in order to restore damaged tissues' functionality. This review offers an overview of the current knowledge concerning hydrogel synthesis and characterization and of the recent achievements in their experimental use in supporting skin, bone, cartilage, and muscle regeneration. The currently available in vitro and in vivo results are of great interest, highlighting the need for carefully designed and controlled preclinical studies and clinical trials to support the transition of these innovative biomaterials from the bench to the bedside.

Indexed as

Biocompatible MaterialsHydrogelsRegenerative MedicineTissue EngineeringAnimalsHumansTissue ScaffoldsBiocompatible MaterialsHydrogelsbiocompatibilitybiomaterialshydrogelregenerative medicinetissue engineeringtissue mechanical properties

Identifiers

PMID39518979
PMCPMC11545898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.