Evidence map›Paper›PMID 39518914›Full record

ArticleInternational journal of molecular sciences2024

Dalanda Wanes, Sherin Al Aoua, Hadeel Shammas, Friederike Walters, Anibh M Das, Sandra Rizk, Hassan Y Naim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dalanda WanesDepartment of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.ORCID 0000-0002-6788-7414
Sherin Al AouaDepartment of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Hadeel ShammasDepartment of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Friederike WaltersDepartment of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Anibh M DasDepartment of Paediatrics, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.ORCID 0000-0001-5884-0852
Sandra RizkDepartment of Natural Sciences, Lebanese American University, Byblos P.O. Box 36, Lebanon.ORCID 0000-0002-4405-5703
Hassan Y NaimDepartment of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.ORCID 0000-0003-4884-8425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Niemann-Pick type C (NPC) disease is an autosomal recessive lysosomal storage disorder where 95% of the cases are caused by mutations in the Niemann-Pick C1 (NPC1) gene. Loss of function in NPC1 mutants trigger the accumulation of cholesterol in late endo-lysosomes and lysosomal dysfunction. The current study examined the potential of polyphenol-rich methanol extracts from

Indexed as

1-DeoxynojirimycinCholesterolFibroblastsNiemann-Pick Disease, Type CPlant ExtractsRutinGolgi ApparatusHumansLysosomesMethanolMutationNiemann-Pick C1 ProteinProtein TransportQuercetin1-DeoxynojirimycinCholesterolMethanolmiglustatNiemann-Pick C1 ProteinPlant ExtractsQuercetinRutincholesterolmiglustat (N-butyldeoxynojirimycin)Niemann–Pick type CquercitrinRosa canina L. methanol extractrutintrafficking

Identifiers

PMID39518914
PMCPMC11547104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.