Evidence map›Paper›PMID 39518880›Full record

ArticleAnimals : an open access journal from MDPI2024

A Retrospective Report of Carprofen Administration as Post-Operative Analgesia Reveals Negative Effects of Recommended Doses.

Zoë Jäckel, Ahmed Adžemović, Benedikt Kloos, Stefanie Hardung, Rita Sanchez-Brandelik, Philippe Coulon, Ilka Diester

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zoë JäckelOptophysiology, Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.ORCID 0000-0002-3481-1448
Ahmed AdžemovićOptophysiology, Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.ORCID 0009-0004-1107-0490
Benedikt KloosCenter for Experimental Models and Transgenic Service, University Medical Center Freiburg, 79104 Freiburg, Germany.ORCID 0000-0003-2486-1756
Stefanie HardungOptophysiology, Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.ORCID 0009-0004-8008-7704
Rita Sanchez-BrandelikFaculty of Medicine, University of Freiburg, 79110 Freiburg, Germany.ORCID 0009-0001-2968-2899
Philippe CoulonOptophysiology, Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.ORCID 0000-0001-8350-5837
Ilka DiesterOptophysiology, Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.ORCID 0000-0001-9362-0986

Funding

Deutsche Forschungsgemeinschaft DI 1908/11-1Federal Ministry of Economics, Science and Arts of Baden-Württemberg BrainLinks-BrainToolsMarie Skłodowska-Curie Actions - European School of Network Neuroscience (euSNN) Innovative Training Network (ETN)
6 · The paper itself

Abstract

Effective pain management in laboratory animals is crucial for both animal welfare and the reliability of scientific research. We retrospectively examined the effects of carprofen as post-operative analgesia in Sprague Dawley rats following stereotactic surgery. Our data indicate that administering carprofen twice daily (5 mg/kg), as currently recommended by

Indexed as

analgesiaanimal welfarelaboratory animalsmultimodal drug administrationrefinementstereotactic surgery

Identifiers

PMID39518880
PMCPMC11544877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.