Evidence map›Paper›PMID 39518866›Full record

ArticleAnimals : an open access journal from MDPI2024

The Multi-Loci Genotypes of the Myostatin Gene Associated with Growth Indicators of Intensively Fattened Lambs of Latvian Sheep.

Ilva Trapina, Daina Kairisa, Samanta Plavina, Nikole Krasnevska, Jegors Paramonovs, Liga Senfelde, Natalia Paramonova

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilva TrapinaGenomics and Bioinformatics, Institute of Biology, Faculty of Medicine and Life Sciences, The University of Latvia, Jelgava Str. 3, LV-1004 Riga, Latvia.ORCID 0000-0002-2165-4770
Daina KairisaInstitute of Agrobiotechnology, Faculty of Agriculture, Latvian University of Life Sciences and Technologies, Liela Street 2, LV-3001 Jelgava, Latvia.
Samanta PlavinaGenomics and Bioinformatics, Institute of Biology, Faculty of Medicine and Life Sciences, The University of Latvia, Jelgava Str. 3, LV-1004 Riga, Latvia.ORCID 0009-0001-0984-4002
Nikole KrasnevskaGenomics and Bioinformatics, Institute of Biology, Faculty of Medicine and Life Sciences, The University of Latvia, Jelgava Str. 3, LV-1004 Riga, Latvia.
Jegors ParamonovsGenomics and Bioinformatics, Institute of Biology, Faculty of Medicine and Life Sciences, The University of Latvia, Jelgava Str. 3, LV-1004 Riga, Latvia.
Liga SenfeldeInstitute of Agrobiotechnology, Faculty of Agriculture, Latvian University of Life Sciences and Technologies, Liela Street 2, LV-3001 Jelgava, Latvia.
Natalia ParamonovaGenomics and Bioinformatics, Institute of Biology, Faculty of Medicine and Life Sciences, The University of Latvia, Jelgava Str. 3, LV-1004 Riga, Latvia.ORCID 0000-0001-6375-3331

Funding

the Latvian Council of Science LZP-2021/1-0489
6 · The paper itself

Abstract

Myostatin (MSTN), a member of the TGFβ superfamily, negatively affects skeletal muscle growth and controls muscle development at stages of pre-natal muscle growth. Marker-assisted selection with molecular markers of the MSTN gene can be used in animal husbandry for higher-quality and more economically profitable lambs. The study aims to identify multi-locus genotypes within the MSTN gene regions as molecular markers for fattening, feed efficiency, and carcass traits in Latvian sheep. This analysis was conducted on 76 intensively fattened male lambs representing six breeds in Latvia. Nine genotypes were identified based on four SNPs in the promoter and exon 1 regions, while six and four SNPs in introns 1 and 2 led to the formation of 14 and 10 genotypes, respectively. Six genotypes identified in the 3'UTR were significantly linked to traits such as birth weight, slaughter yield, muscle development, fat depth, average daily gain, dry matter intake, and feed efficiency. Genotypes of intron 1 were associated with slaughter yield, while genotypes of intron 2 were linked to fat depth, dry matter intake, and residual weight gain. The study concludes that MSTN gene SNPs can be used in selection to enhance sheep breeds in Latvia and improve economic outcomes for breeders.

Indexed as

feed efficiencygenetic markersintensive fatteningLatvian sheepmulti-loci genotypemyostatin

Identifiers

PMID39518866
PMCPMC11545172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.