Evidence map›Paper›PMID 39518686›Full record

ReviewJournal of clinical medicine2024

Association Between Thyrotoxicosis and Cerebral Venous Thrombosis.

Margherita Paccagnella, Anna Pizzo, Veronica Calabrò, Valerio Velardi, Bruno Fabris, Stella Bernardi

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Margherita PaccagnellaDepartment of Medical Surgical and Health Sciences, University of Trieste, Cattinara Teaching Hospital Strada di Fiume 449, 34149 Trieste, Italy.
Anna PizzoDepartment of Medical Surgical and Health Sciences, University of Trieste, Cattinara Teaching Hospital Strada di Fiume 449, 34149 Trieste, Italy.
Veronica CalabròUnit Endocrinology Medicina Clinica, ASUGI, Cattinara Teaching Hospital Strada di Fiume 449, 34149 Trieste, Italy.
Valerio VelardiDepartment of Medical Surgical and Health Sciences, University of Trieste, Cattinara Teaching Hospital Strada di Fiume 449, 34149 Trieste, Italy.ORCID 0009-0001-4516-8427
Bruno FabrisDepartment of Medical Surgical and Health Sciences, University of Trieste, Cattinara Teaching Hospital Strada di Fiume 449, 34149 Trieste, Italy.
Stella BernardiDepartment of Medical Surgical and Health Sciences, University of Trieste, Cattinara Teaching Hospital Strada di Fiume 449, 34149 Trieste, Italy.ORCID 0000-0002-7429-3075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyrotoxicosis appears to be a predisposing factor for cerebral venous thrombosis (CVT), which is a rare but important cause of stroke in young adults. The presentation of CVT is highly variable, ranging from a history of headaches (in the majority of cases) to deep coma, with the latter requiring invasive neurosurgical decompression. Although the long-term outcomes of CVT are favorable, multicenter cohort studies have shown that death may occur in up to 4% of cases in the acute phase and 8-10% of cases in the long term. It has been argued that the substantial decrease in mortality in patients with CVT that has been observed during the past few decades may be the result of an increased awareness of CVT among clinicians. Given that thyrotoxicosis is a risk factor for CVT, clinicians (and endocrinologists) should be alert to the possibility of CVT in patients with thyroid disease in order to prevent it whenever possible or treat it promptly. In this review, we provide an updated overview of the characteristics of patients with thyrotoxicosis who presented with CVT, the underlying mechanisms, and a few tips for clinicians.

Indexed as

case reportcerebral venous thrombosisGraves’ diseasemechanismsthyrotoxicosis

Identifiers

PMID39518686
PMCPMC11546735

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.