Evidence map›Paper›PMID 39518646›Full record

ArticleJournal of clinical medicine2024

The Effects of Systemic Tranexamic Acid Administration on Drainage Volume, Duration of Drain Placement, and Length of Hospital Stay in Skin- and Nipple-Sparing Mastectomies with Immediate Expander-Based Breast Reconstruction.

Leon Guggenheim, Sara Magni, Armin Catic, Alberto Pagnamenta, Yves Harder, Daniel Schmauss

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07131592 (The Effect of Tranexamic Acid on Drainage Volume and Time to Drain Removal in Reduction Mammaplasty Patients), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07131592 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Tranexamic Acid on Drainage Volume and Time to Drain Removal in Reduction Mammaplasty Patients

TypeinterventionalSponsorMassachusetts General HospitalRan2025 to 2027Enrolled160ConditionsDrain Output After Breast Reduction Surgery, Breast ReductionsArmsIV TXA, Topical TXA, Topical saline
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Complications, patient satisfaction, clinical outcomes, and aesthetic outcomes of nipple-sparingTranslational breast cancer research : a journal focusing on translational research in breast cancer · 2026
    Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leon GuggenheimFaculty of Biomedical Sciences, Università della Svizzera Italiana, CH-6900 Lugano, Switzerland.
Sara MagniDepartment of Plastic, Reconstructive and Aesthetic Surgery, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), CH-6900 Lugano, Switzerland.
Armin CaticFaculty of Biomedical Sciences, Università della Svizzera Italiana, CH-6900 Lugano, Switzerland.ORCID 0000-0001-7833-6418
Alberto PagnamentaClinical Trial Unit (CTU), Ente Ospedaliero Cantonale (EOC), CH-6900 Lugano, Switzerland.ORCID 0000-0001-7241-0111
Yves HarderDepartment of Plastic, Reconstructive and Aesthetic Surgery and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), CH-1011 Lausanne, Switzerland.ORCID 0000-0002-2557-249X
Daniel SchmaussFaculty of Biomedical Sciences, Università della Svizzera Italiana, CH-6900 Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

complicationsdrainageexpandermastectomysystemic tranexamic acidtranexamic acid

Identifiers

PMID39518646
PMCPMC11546841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.