Evidence map›Paper›PMID 39518362›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Predictive and Explainable Artificial Intelligence for Neuroimaging Applications.

Sekwang Lee, Kwang-Sig Lee

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sekwang LeeDepartment of Physical Medicine and Rehabilitation, Anam Hospital, Korea University College of Medicine, Seoul 02841, Republic of Korea.ORCID 0000-0002-3044-2673
Kwang-Sig LeeAI Center, Anam Hospital, Korea University College of Medicine, Seoul 02841, Republic of Korea.ORCID 0000-0002-0576-0098

Funding

Korea Health Industry Development Institute HI22C1302
6 · The paper itself

Abstract

backgroundThe aim of this review is to highlight the new advance of predictive and explainable artificial intelligence for neuroimaging applications.

methodsData came from 30 original studies in PubMed with the following search terms: "neuroimaging" (title) together with "machine learning" (title) or "deep learning" (title). The 30 original studies were eligible according to the following criteria: the participants with the dependent variable of brain image or associated disease; the interventions/comparisons of artificial intelligence; the outcomes of accuracy, the area under the curve (AUC), and/or variable importance; the publication year of 2019 or later; and the publication language of English.

resultsThe performance outcomes reported were within 58-96 for accuracy (%), 66-97 for sensitivity (%), 76-98 for specificity (%), and 70-98 for the AUC (%). The support vector machine and the convolutional neural network registered the best performance (AUC 98%) for the classifications of low- vs. high-grade glioma and brain conditions, respectively. Likewise, the random forest delivered the best performance (root mean square error 1) for the regression of brain conditions. The following factors were discovered to be major predictors of brain image or associated disease: (demographic) age, education, sex; (health-related) alpha desynchronization, Alzheimer's disease stage, CD4, depression, distress, mild behavioral impairment, RNA sequencing; (neuroimaging) abnormal amyloid-β, amplitude of low-frequency fluctuation, cortical thickness, functional connectivity, fractal dimension measure, gray matter volume, left amygdala activity, left hippocampal volume, plasma neurofilament light, right cerebellum, regional homogeneity, right middle occipital gyrus, surface area, sub-cortical volume.

conclusionPredictive and explainable artificial intelligence provide an effective, non-invasive decision support system for neuroimaging applications.

Indexed as

explainable artificial intelligenceneuroimagingpredictive artificial intelligence

Identifiers

PMID39518362
PMCPMC11545799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.