Evidence map›Paper›PMID 39518297›Full record

ArticlePolymers2024

Study of Polysulfone-Impregnated Hydroxyapatite for Ultrafiltration in Whey Protein Separation.

Tutik Sriani, Muslim Mahardika, Budi Arifvianto, Farazila Yusof, Yudan Whulanza, Gunawan Setia Prihandana, Ario Sunar Baskoro

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tutik SrianiDepartment of Research and Development, PT. Global Meditek Utama-IITOYA, Sardonoharjo, Ngaglik, Sleman, Yogyakarta 55581, Indonesia.
Muslim MahardikaDepartment of Mechanical and Industrial Engineering, Faculty of Engineering, Universitas Gadjah Mada, Jalan Grafika No. 2, Yogyakarta 55281, Indonesia.
Budi ArifviantoDepartment of Mechanical and Industrial Engineering, Faculty of Engineering, Universitas Gadjah Mada, Jalan Grafika No. 2, Yogyakarta 55281, Indonesia.ORCID 0000-0003-4039-4641
Farazila YusofCentre of Advanced Manufacturing & Material Processing (AMMP Centre), Department of Mechanical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0001-6034-0996
Yudan WhulanzaDepartment of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI, Depok 16425, Indonesia.ORCID 0000-0002-1541-2118
Gunawan Setia PrihandanaDepartment of Industrial Engineering, Faculty of Advanced Technology and Multidiscipline, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno, Surabaya 60115, Indonesia.ORCID 0000-0003-3709-2036
Ario Sunar BaskoroDepartment of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI, Depok 16425, Indonesia.

Funding

Universitas Airlangga 958/UN3.LPPM/PT.01.03/2023Universitas Gadjah Mada 2692/UN1/DITLIT/Dit-Lit/PT.01.03/2023Universitas Indonesia NKB-1078/UN2.RST/HKP.05.00/2023
6 · The paper itself

Abstract

Polysulfone (Psf) ultrafiltration flat-sheet membranes were modified with hydroxyapatite (HA) powder during preparation using the wet-phase inversion method. HA was incorporated to enhance the protein separation capabilities. The asymmetric Psf membranes were synthesized using NMP as the solvent. Through Scanning Electron Microscopy (SEM) analysis, it was revealed that HA was distributed across the membrane. Incorporating HA led to higher flux, the improved rejection of protein, and enhanced surface hydrophilicity. The permeability flux increased with HA concentration, peaking at 0.3 wt.%, resulting in a 38% improvement to 65 LMH/bar. Whey protein separation was evaluated using the model proteins BSA and lysozyme, representing α-Lactalbumin. The results of protein rejection for the blend membranes indicated that the rejection rates for BSA and lysozyme increased to 97.2% and 73%, respectively. Both the native and blend membranes showed similar BSA rejection rates; however, the blend membranes demonstrated better performance in lysozyme separation, indicating superior selectivity compared to native membranes. The modified membranes exhibited improved hydrophilicity, with water contact angles decreasing from 66° to 53°, alongside improved antifouling properties, indicated by a lower flux decline ratio value. This simple and economical modification method enhances permeability without sacrificing separation efficiency, hence facilitating the scalability of membrane production in the whey protein separation industry.

Indexed as

clean waterhydroxyapatitepolysulfoneprotein separationultrafiltrationwhey

Identifiers

PMID39518297
PMCPMC11548170

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.