Evidence map›Paper›PMID 39518105›Full record

ArticleCancers2024

Grad-CAM Enabled Breast Cancer Classification with a 3D Inception-ResNet V2: Empowering Radiologists with Explainable Insights.

Fatma M Talaat, Samah A Gamel, Rana Mohamed El-Balka, Mohamed Shehata, Hanaa ZainEldin

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fatma M TalaatFaculty of Artificial Intelligence, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.ORCID 0009-0007-2807-1555
Samah A GamelElectronics and Communication Engineering Department, Faculty of Engineering, Horus University Egypt, Damietta 34518, Egypt.
Rana Mohamed El-BalkaComputers and Control Systems Engineering Department, Faculty of Engineering, Mansoura University, Mansoura 35516, Egypt.
Mohamed ShehataComputers and Control Systems Engineering Department, Faculty of Engineering, Mansoura University, Mansoura 35516, Egypt.ORCID 0000-0001-6640-6183
Hanaa ZainEldinComputers and Control Systems Engineering Department, Faculty of Engineering, Mansoura University, Mansoura 35516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BCa) poses a severe threat to women's health worldwide as it is the most frequently diagnosed type of cancer and the primary cause of death for female patients. The biopsy procedure remains the gold standard for accurate and effective diagnosis of BCa. However, its adverse effects, such as invasiveness, bleeding, infection, and reporting time, keep this procedure as a last resort for diagnosis. A mammogram is considered the routine noninvasive imaging-based procedure for diagnosing BCa, mitigating the need for biopsies; however, it might be prone to subjectivity depending on the radiologist's experience. Therefore, we propose a novel, mammogram image-based BCa explainable AI (BCaXAI) model with a deep learning-based framework for precise, noninvasive, objective, and timely manner diagnosis of BCa. The proposed BCaXAI leverages the Inception-ResNet V2 architecture, where the integration of explainable AI components, such as Grad-CAM, provides radiologists with valuable visual insights into the model's decision-making process, fostering trust and confidence in the AI-based system. Based on using the DDSM and CBIS-DDSM mammogram datasets, BCaXAI achieved exceptional performance, surpassing traditional models such as ResNet50 and VGG16. The model demonstrated superior accuracy (98.53%), recall (98.53%), precision (98.40%), F1-score (98.43%), and AUROC (0.9933), highlighting its effectiveness in distinguishing between benign and malignant cases. These promising results could alleviate the diagnostic subjectivity that might arise as a result of the experience-variability between different radiologists, as well as minimize the need for repetitive biopsy procedures.

Indexed as

BCaXAIbreast cancer diagnosisdeep learningexplainable AIGrad-CAMmammogram imaging

Identifiers

PMID39518105
PMCPMC11544836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.