ReviewCancers2024
The Evidence Base for Circulating Tumor DNA-Methylation in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.
Abstract readReview
In one paragraph
Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Diagnostic and Prognostic Roles of Blood-Based Immune Biomarkers in Non-Small Cell Lung Cancer: An Umbrella Review of Systematic Reviews and Meta-Analyses.Life (Basel, Switzerland) · 2026Review
- Exploring genomic analysis and methylome profiling in longitudinal series of p.G12C KRAS mutated NSCLC patients treated with sotorasib.The journal of liquid biopsy · 2026Article
- The critical role of accurate neoplastic cell percentage (NCP) assessment: investigating targeted training strategies for pulmonary biopsy and cytology specimens.Virchows Archiv : an international journal of pathology · 2026Article
- Methylated circulating tumor DNA: technical challenges and clinical applications in non-small cell lung cancer patients-a narrative review.Translational lung cancer research · 2026Review
- Article
- Liquid biopsy biomarkers for cancer detection, treatment monitoring, and clinical outcome prediction.Frontiers in cell and developmental biology · 2026Review
- Beyond genes: a clinician's guide to epigenetics.Breathe (Sheffield, England) · 2025Review
- Review
- Lung cancer biobanking in Australia: challenges and future directions.The Medical journal of Australia · 2025Article
- Long interspersed nuclear element 1 methylation in non-small cell lung cancer: implications for diagnosis, prognosis, and therapeutic targeting.Cell communication and signaling : CCS · 2025Review
- Identification and single-cell analysis of prognostic genes related to mitochondrial and neutrophil extracellular traps in bladder cancer.Scientific reports · 2025Article
- Study on the regulation mechanism of TBX5 gene and Gegen Qinlian decoction on colorectal cancer.Frontiers in oncology · 2025Article
- Application of Liquid Biopsy Technology in Lung Cancer: A Bibliometric Study and Visualization Analysis.Cancer management and research · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Debora MaffeoMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0009-0006-0549-4953
Angela RinaMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0009-0009-6469-2564
Viola Bianca SerioMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-4566-6124
Athina MarkouLab of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15772 Athens, Greece.ORCID 0000-0001-7760-9701
Tomasz PowrózekDepartment of Human Physiology, University of Lublin, 20080 Lublin, Poland.ORCID 0000-0001-9174-8548
Vera ConstâncioCancer Biology and Epigenetics Group, Research Center (CI-IPOP)/CI-IPOP@RISE (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC), 4200-072 Porto, Portugal.ORCID 0000-0002-3151-0367
Sandra P NunesCancer Biology and Epigenetics Group, Research Center (CI-IPOP)/CI-IPOP@RISE (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC), 4200-072 Porto, Portugal.
Carmen JerónimoCancer Biology and Epigenetics Group, Research Center (CI-IPOP)/CI-IPOP@RISE (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC), 4200-072 Porto, Portugal.ORCID 0000-0003-4186-5345
Alfonso CalvoProgram in Solid Tumors, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), Instituto de Investigación Sanitaria de Navarra (IDISNA), Department of Pathology, Anatomy and Physiology, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-4074-4242
Francesca MariUOC Laboratorio di Assistenza e Ricerca Traslazionale, Dipartimento di Terapie cellulari, Ematologia e Medicina di Laboratorio, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.ORCID 0000-0003-1992-1654
Elisa FrullantiMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-5634-031X
Diletta RosatiMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Maria PalmieriMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3014-1552
Funding
NextGenerationEU of PNRR "Piano Nazionale di Ripresa e Resilienza" Missione 4 Componente 2 - M4C2a - Project THE - Tuscany Health Ecosystem - SPOKE 6 - CUP B63C22000680007 (MILESTONE n. 6.3.2: Innovative tools for target genes, disease pathways and therap CUP B63C22000680007
Abstract
PubMed holds no abstract for this paper.
Indexed as
circulating free DNAearly diagnosismethylationnon-small cell lung cancer
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.