Evidence map›Paper›PMID 39517878›Full record

ArticleSensors (Basel, Switzerland)2024

Radiofrequency Enhancer to Recover Signal Dropouts in 7 Tesla Diffusion MRI.

Varun Subramaniam, Andrew Frankini, Ameen Al Qadi, Mackenzie T Herb, Gaurav Verma, Bradley N Delman, Priti Balchandani, Akbar Alipour

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Varun SubramaniamDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-3005-8006
Andrew FrankiniDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Ameen Al QadiDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mackenzie T HerbDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-7783-0414
Gaurav VermaDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Bradley N DelmanDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Priti BalchandaniDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Akbar AlipourDepartment of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-7981-6808

Funding

7T Neurosurgical Mapping Protocol for Endoscopic Resection of Skull Base TumorsR01CA202911 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BALCHANDANI, PRITI · 2016 to 2020
$2.1M
Visualizing trigeminal neuralgia at 7 Tesla: Advancing etiological understanding and improving future clinical imaging protocolsR56DE030680 · NIDCR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BALCHANDANI, PRITI · 2022 to 2022
$532k
NCI NIH HHS R01 CA202911NIDCR NIH HHS R56 DE030680NIH HHS K01AG075178, R01CA202911
6 · The paper itself

Abstract

Diffusion magnetic resonance imaging (dMRI) allows for a non-invasive visualization and quantitative assessment of white matter architecture in the brain by characterizing restrictions on the random motion of water molecules. Ultra-high field MRI scanners, such as those operating at 7 Tesla (7T) or higher, can boost the signal-to-noise ratio (SNR) to improve dMRI compared with what is attainable at conventional field strengths such as 3T or 1.5T. However, wavelength effects at 7T cause reduced transmit magnetic field efficiency in the human brain, mainly in the posterior fossa, manifesting as signal dropouts in this region. Recently, we reported a simple approach of using a wireless radiofrequency (RF) surface array to improve transmit efficiency and signal sensitivity at 7T. In this study, we demonstrate the feasibility and effectiveness of the RF enhancer in improving in vivo dMRI at 7T. The electromagnetic simulation results demonstrated a 2.1-fold increase in transmit efficiency with the use of the RF enhancer. The experimental results similarly showed a 1.9-fold improvement in transmit efficiency and a 1.4-fold increase in normalized SNR. These improvements effectively mitigated signal dropouts in regions with inherently lower SNR, such as the cerebellum, resulting in a better depiction of principal fiber orientations and an enhanced visualization of extended tracts.

Indexed as

BrainDiffusion Magnetic Resonance ImagingRadio WavesSignal-To-Noise RatioHumansImage Processing, Computer-AssistedWhite Matterdiffusion MRIinductive couplingRF resonatorultra-high field MRI

Identifiers

PMID39517878
PMCPMC11548241

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.