Evidence map›Paper›PMID 39517401›Full record

ArticleHealthcare (Basel, Switzerland)2024

Evaluation of Periodontitis and

Anna Antonacci, Cinzia Bizzoca, Giuseppe Barile, Valeria Andriola, Leonardo Vincenti, Nicola Bartolomeo, Antonia Abbinante, Germano Orrù, Massimo Corsalini

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Periodontitis, colorectal cancer and associated factors: A cross-sectional study.Journal of clinical and experimental dentistry · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna AntonacciDepartment of Interdisciplinary Medicine, 'Aldo Moro', University of Bari, 70100 Bari, Italy.
Cinzia BizzocaDepartment of General Surgery "Ospedaliera", Polyclinic Hospital of Bari, 70100 Bari, Italy.ORCID 0000-0003-0410-0490
Giuseppe BarileDepartment of Interdisciplinary Medicine, 'Aldo Moro', University of Bari, 70100 Bari, Italy.
Valeria AndriolaDepartment of General Surgery "Ospedaliera", Polyclinic Hospital of Bari, 70100 Bari, Italy.
Leonardo VincentiGeneral Surgery Unit, National Institute of Gastroenterology IRCCS Saverio de Bellis, Research Hospital, Via Turi 27, 0013 Bari, Italy.
Nicola BartolomeoDepartment of Interdisciplinary Medicine, 'Aldo Moro', University of Bari, 70100 Bari, Italy.ORCID 0000-0002-8540-4615
Antonia AbbinanteDepartment of Interdisciplinary Medicine, 'Aldo Moro', University of Bari, 70100 Bari, Italy.ORCID 0000-0003-4294-0941
Germano OrrùDepartment of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-1032-4431
Massimo CorsaliniDepartment of General Surgery "Ospedaliera", Polyclinic Hospital of Bari, 70100 Bari, Italy.ORCID 0000-0002-0521-1363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriodontitis has been associated with an increased risk of CRC, as well as a worse prognosis due to increased inflammation mediators and carcinogenic factors. Moreover, direct and indirect virulence factors from periodontal pathogens, such as MATERIALS AND

methodsPatients affected by CRC underwent dental examination and periodontal charting with the "North Carolina" probe to assess the presence and stage of periodontitis, according to the new classification of periodontal diseases of the World Workshop of the European Federation of Periodontology (EFP) and the American Academy of Periodontology (AAP) 2017.

resultsPeriodontal disease was found in 94.3% of I/II CRC stage patients and 100% of III/IV CRC stage patients. Severe periodontitis was found in 76% of the advanced CRC stage and 87.9% of patients with initial CRC, while initial periodontitis was found in 12.1% of initial CRC and 24% of late CRC stages, respectively, without significant differences.

conclusionsPeriodontal disease showed a high prevalence among CRC patients. Moreover, severe periodontitis has a higher prevalence in CRC patients compared to initial periodontitis.

Indexed as

colorectal cancerF. nucleatumoral dysbiosisperiodontitisvolatile sulfur compounds

Identifiers

PMID39517401
PMCPMC11545387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.