Evidence map›Paper›PMID 39516548›Full record

ArticleScientific reports2024

Dermal macrophages control tactile perception under physiological conditions via NGF signaling.

Tatsuhide Tanaka, Ayami Isonishi, Mitsuko Banja, Rikuto Yamamoto, Masaki Sonobe, Emiko Okuda-Ashitaka, Hidemasa Furue, Hiroaki Okuda, Kouko Tatsumi, Akio Wanaka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tatsuhide TanakaDepartment of Anatomy and Neuroscience, Nara Medical University, Kashihara, Nara, Japan. ttanaka@naramed-u.ac.jp.
Ayami IsonishiDepartment of Anatomy and Neuroscience, Nara Medical University, Kashihara, Nara, Japan.
Mitsuko BanjaDepartment of Anatomy and Neuroscience, Nara Medical University, Kashihara, Nara, Japan.
Rikuto YamamotoDepartment of Biomedical Engineering, Osaka Institute of Technology, Osaka, Japan.
Masaki SonobeDepartment of Anatomy and Neuroscience, Nara Medical University, Kashihara, Nara, Japan.
Emiko Okuda-AshitakaDepartment of Biomedical Engineering, Osaka Institute of Technology, Osaka, Japan.
Hidemasa FurueDepartment of Neurophysiology, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Hiroaki OkudaDepartment of Functional Morphology, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Kouko TatsumiDepartment of Anatomy and Neuroscience, Nara Medical University, Kashihara, Nara, Japan.
Akio WanakaDepartment of Anatomy and Neuroscience, Nara Medical University, Kashihara, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrated previously that sorting nexin 25 (SNX25) in nerve-associated macrophages plays critical roles in pain sensation by regulating tissue NGF content under both physiological and neuropathic conditions. In the present study, we apply the SNX25-NGF paradigm to tactile perception by showing that Snx25

Indexed as

MacrophagesMice, KnockoutNerve Growth FactorSignal TransductionSorting NexinsAnimalsCalcitonin Gene-Related PeptideDermisMaleMiceTouch PerceptionCalcitonin Gene-Related PeptideNerve Growth FactorSorting NexinsDermal macrophageNGFSNX25Tactile perception

Identifiers

PMID39516548
PMCPMC11549316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.