ArticleNPJ science of food2024
Identification strategy of wild and cultivated Astragali Radix based on REIMS combined with two-dimensional LC-MS.
Article in NPJ science of food, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Integrated strategy for multivariate quality description ofFood chemistry: X · 2026Article
- A polarity-based two-dimensional LC-MS/MS distribution strategy combined with ion identity molecular networking for enhanced metabolite annotation in Astragalus Radix species.Analytical and bioanalytical chemistry · 2026Article
- Application of biosensors in research of traditional Chinese medicine: a systematic review.Chinese medicine · 2026Review
- A novel method for real-time adulteration identification of heated-honey processed Astragali radix using REIMS-iKnife and its regulatory effects on gut microbiota, SCFAs, and immune function in spleen-deficient rats.Frontiers in pharmacology · 2026Article
- Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research.Mass spectrometry reviewsReview
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Authors and funding
6 authors.
Funding
Abstract
A rapid and real-time method was established based on the combination of rapid evaporative ionization mass spectrometry (REIMS) and two-dimensional liquid chromatography mass spectrometry (2DLC-MS) for identification of wild Astragali Radix (WAR) and cultivated AR (CAR). The samples were analyzed under ambient ionization without time-consuming sample preparation. The phenotypic data of WAR and CAR were used to develop a real-time recognition model. Subsequently, the compounds in these two species were comprehensively characterized based on 2DLC-MS, and 45 different compounds were screened out by multivariate statistical analysis. A semi-quantitative method for 45 different compounds was established based on ultrahigh-performance liquid chromatography/quadrupole-linear ion trap mass spectrometry (UHPLC-QTRAP-MS). The results showed that the relative content of most compounds in WAR was higher than in CAR. In summary, the method has demonstrated remarkable performance in distinguishing between WAR and CAR, providing a reference in the field of traditional Chinese medicine (TCM) analysis and identification.
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Registered trials
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