Evidence map›Paper›PMID 39516451›Full record

ArticleJournal of nephrology2025

Predictors of acute kidney injury in chronic kidney disease patients treated for cardiovascular disease in the cardiac intensive care unit (MORCOR-TURK subgroup analysis).

Omer Dogan, Aybike Gul Tasdelen Acar, Mural Gul, Ozgen Safak, Sefa Erdi Omur, Adem Atıcı, Hasan Ali Barman, Muhammed Erkam Cengil, Ahmet Seyda Yilmaz, İbrahim Ersoy

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Omer DoganDepartment of Cardiology, Istanbul University-Cerrahpaşa Institute of Cardiology, Istanbul, Turkey. omrdgn123@gmail.com.ORCID 0000-0003-2279-6110
Aybike Gul Tasdelen AcarDepartment of Cardiology, Istanbul University-Cerrahpaşa Institute of Cardiology, Istanbul, Turkey.
Mural GulFaculty of Medicine, Department of Cardiology, Aksaray University, Aksaray, Turkey.
Ozgen SafakFaculty of Medicine, Department of Cardiology, Balikesir University, Balikesir, Turkey.
Sefa Erdi OmurFaculty of Medicine, Department of Cardiology, Tokat Gaziosmanpasa University, Tokat, Turkey.
Adem AtıcıDepartment of Cardiology, Istanbul Medeniyet UniversityFaculty of MedicineGoztepe Training and Research Hospital, Istanbul, Turkey.
Hasan Ali BarmanDepartment of Cardiology, Istanbul University-Cerrahpaşa Institute of Cardiology, Istanbul, Turkey.
Muhammed Erkam CengilDepartment of Cardiology, Ministry of Health, Osmaniye State Hospital, Osmaniye, Turkey.
Ahmet Seyda YilmazDepartment of Cardiology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize, Turkey.
İbrahim ErsoyDepartment of Cardiology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a common complication in chronic kidney disease (CKD) patients in the cardiac intensive care unit (cardiac ICU). In this study, we aimed to identify predictors of AKI in CKD patients treated in the cardiac ICU for cardiovascular diseases.

methodsThe MORCOR-TURK trial was conducted as a multicenter, prospective, cross-sectional, and noninterventional investigation. A total of 3157 patients treated in the cardiac ICU were enrolled from 50 centers over the course of one month. In this subgroup analysis, 615 patients with CKD treated in the cardiac ICU for cardiovascular disease were included in the study. The primary outcome of this study was the development of AKI. During hospitalization, patients who developed AKI were identified.

resultsAKI developed in 288 patients (46%). After multivariable analysis, decompensated heart failure (OR: 3.72, p = 0.005), primary percutaneous coronary intervention (OR: 3.75, p = 0.004), non-primary percutaneous coronary intervention (OR: 2.85, p = 0.033), troponin levels (OR: 1.04, p = 0.031), and need for mechanical ventilation (OR: 3.11, p < 0.001) were identified as independent predictors of AKI development in CKD patients.

conclusionOur efforts to identify AKI predictors in cardiac ICU patients with CKD have yielded directly applicable results in clinical practice. AKI can be prevented by developing personalized strategies to follow up and treat cardiac ICU patients with CKD who have decompensated heart failure, are undergoing percutaneous coronary intervention (primary and non-primary), have high troponin levels, and need mechanical ventilation.

Indexed as

Acute Kidney InjuryCardiovascular DiseasesCoronary Care UnitsRenal Insufficiency, ChronicAgedCross-Sectional StudiesFemaleHumansIntensive Care UnitsMaleMiddle AgedPercutaneous Coronary InterventionProspective StudiesRespiration, ArtificialRisk AssessmentRisk FactorsTroponinAcute kidney injuryChronic kidney diseaseClinical predictorsCoronary intensive care unit

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.