Evidence map›Paper›PMID 39516384›Full record

ArticlePediatric radiology2024

Comparison of tibial and femoral physeal diffusion tensor imaging in adolescents.

Laura Santos, Andressa Guariento, Sogol Moustoufi-Moab, Jie Nguyen, Rumana Tokaria, Jose Maria Raya, David Zurakowski, Sachin Jambawalikar, Diego Jaramillo

Abstract readComparative Study
In one paragraph

Article in Pediatric radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura SantosColumbia University Medical Center, 622 W 168Th St, New York, NY, 10032, USA. ls3865@cumc.columbia.edu.ORCID 0009-0008-0556-4901
Andressa GuarientoChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Sogol Moustoufi-MoabChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Jie NguyenChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Rumana TokariaColumbia University Medical Center, 622 W 168Th St, New York, NY, 10032, USA.
Jose Maria RayaNew York University Medical Center, New York, NY, USA.
David ZurakowskiChildren's Hospital, Boston, MA, USA.
Sachin JambawalikarColumbia University Medical Center, 622 W 168Th St, New York, NY, 10032, USA.
Diego JaramilloHospital for Special Surgery, New York, NY, USA.

Funding

Understanding Skeletal Growth Using Diffusion Tensor Imaging of the Physis and MetaphysisR01HD104720 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JAMBAWALIKAR, SACHIN · 2021 to 2025
$3.1M
NICHD NIH HHS R01 HD104720
6 · The paper itself

Abstract

backgroundDistal femoral diffusion tensor imaging (DTI) is a predictor of height gain but it is uncertain whether DTI can demonstrate differences in growth potential between the tibia and femur.

objectiveTo explore the differences in structure and growth potential of the proximal tibia physeal-metaphyseal complex compared to those of the distal femur through DTI tractographic characterization and DTI metric comparison. MATERIALS AND

methodsProspective cross-sectional study involved 108 healthy children (59 females) aged 8-14 years (females) and 10-16 years (males) around the growth spurt. We acquired knee DTI once at 3 T with b-values of 0 s/mm

resultsProximal tibial tracts were more numerous in the central physis, whereas distal femoral tracts predominated peripherally. Tract volume rose and fell during adolescence and peaked earlier in females (140-160 months vs. 160-180 months, P=0.02). At maximal height velocity (160 months), tibial tract volume (5.43 cc) was 37.4% of total knee tract volume (14.53 cc). Tibial fractional anisotropy decreased and then increased, both earlier than the femur.

conclusionProximal tibial and distal femoral tract distributions differ. The tibia accounts for 37.4% of total knee tract volume during maximal height velocity. Tract volumes rise and fall, earlier in females. Tibiofemoral ratios of DTI metrics resemble known ratios of growth rates between tibia and femur.

Indexed as

Diffusion Tensor ImagingFemurTibiaAdolescentChildCross-Sectional StudiesFemaleHumansMaleProspective StudiesDiffusion tensor imagingGrowthKneePhyses

Identifiers

PMID39516384
PMCPMC11638376

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.