Evidence map›Paper›PMID 39516353›Full record

Trial reportApplied psychophysiology and biofeedback2025

Changes in Negative Emotions Across Five Weeks of HRV Biofeedback Intervention were Mediated by Changes in Resting Heart Rate Variability.

Heidi Jung, Hyun Joo Yoo, Paul Choi, Kaoru Nashiro, Jungwon Min, Christine Cho, Julian F Thayer, Paul Lehrer, Mara Mather

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Applied psychophysiology and biofeedback, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  3. Review
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  10. The A52 Breath Method: A Narrative Review of Breathwork for Mental Health and Stress Resilience.Stress and health : journal of the International Society for the Investigation of Stress · 2025
    Review
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Heidi JungLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA.
Hyun Joo YooLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA.
Paul ChoiLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA.
Kaoru NashiroLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA.
Jungwon MinLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA.
Christine ChoLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA.
Julian F ThayerUniversity of California, Irvine, Irvine, CA, 92697, USA.
Paul LehrerRutgers University, Piscataway, 08854, USA.
Mara MatherLeonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave., Los Angeles, CA, 90089, USA. mara.mather@usc.edu.

Funding

Why Does Heart Rate Variability Matter for Emotion RegulationR01AG057184 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MATHER, MARA · 2017 to 2021
$2.1M
NIA NIH HHS R01 AG057184NIH HHS R01AG057184
6 · The paper itself

Abstract

Resting heart rate variability (HRV) is typically higher in those with better emotional well-being. In the current study, we examined whether changes in resting HRV mediated changes in negative emotions during a 7-week clinical trial of HRV biofeedback. Younger and older adults were randomly assigned to one of two daily biofeedback practices for 5 weeks: (1) engage in slow-paced breathing to increase the amplitude of oscillations in heart rate at their breathing frequency (Osc+); or (2) engage in self-selected strategies to decrease heart rate oscillations (Osc-). We assessed negative emotion using the State Anxiety Inventory (SAI) and Profile of Mood States (POMS). Resting HRV at pre-intervention was significantly higher among those with lower negative emotion scores. Those participants showing greater increases in resting HRV showed greater decreases in negative emotion. In a mediation model with all participants, resting HRV changes significantly mediated the relationship between training performance (i.e., heart rate oscillation during practice sessions) and changes in negative emotion. However, additional analyses revealed this mediation effect was significantly moderated by condition and was only significant in the Osc+ condition. Thus, resting HRV changes mediated how biofeedback to increase amplitude of heart rate oscillations reduced negative emotion.

Indexed as

AffectBiofeedback, PsychologyEmotionsHeart RateAdultAgedEmotional RegulationFemaleHumansMaleMiddle AgedYoung AdultBiofeedbackEmotionHeart rate variabilitySlow-paced breathing

Identifiers

PMID39516353
PMCPMC11882736

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.