Evidence map›Paper›PMID 39516326›Full record

SynthesisJournal of cancer survivorship : research and practice2026

Combined healthy lifestyle factors and psychosocial outcomes among cancer survivors: a systematic review and meta-analysis.

Chunsu Zhu, Zhiwei Lian, Volker Arndt, Melissa S Y Thong

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chunsu ZhuUnit of Cancer Survivorship, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6657-3184
Zhiwei LianUnit of Cancer Survivorship, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1087-6981
Volker ArndtUnit of Cancer Survivorship, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9320-8684
Melissa S Y ThongUnit of Cancer Survivorship, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. m.thong@dkfz-heidelberg.de.ORCID http://orcid.org/0000-0002-6987-705X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review aims to summarize the associations between combined healthy lifestyles and psychosocial outcomes (health-related quality of life (HRQOL), depression, anxiety, psychological distress (PD), and posttraumatic stress disorder (PTSD)) among cancer survivors.

methodsPubMed, Web of Science, Cochrane Library, and EMBASE were searched for observational and interventional studies examining healthy lifestyle scores (HLS, calculated by a combination of at least three lifestyles) and psychosocial outcomes among cancer survivors from inception to April 2024. A minimum of two studies with the same study design were pooled using random effects models.

resultsTwenty-one studies (44,812 survivors) were included. Of all studies, 16 of which were included in meta-analysis. The pooling of cross-sectional evidence shows significant association between HLS and overall, physical, and psychosocial HRQOL. Significance was only observed for overall and physical HRQOL but not for psychosocial HRQOL in cohort studies. The estimations and 95% confidence interval (CI) with 1-point increase in HLS were 1.47 (0.83-2.12) and 1.42 (0.19-2.65) for overall and physical HRQOL, respectively. The evidence from interventional studies also indicated that interventions on multiple lifestyles have positive effects on the physical but not psychosocial HRQOL. Despite the limited number of studies, significant associations were found between HLS and depression, anxiety, PD, and PTSD.

conclusionsAlthough evidence is limited, we found that the combination of multiple healthier lifestyles is associated with better psychosocial outcomes in cancer survivors. IMPLICATIONS FOR CANCER SURVIVORS: This review underscores the potential for adhering to multiple healthy lifestyles to improve psychosocial outcomes and enhance HRQOL for cancer survivors.

Indexed as

Cancer SurvivorsHealthy LifestyleNeoplasmsQuality of LifeAnxietyDepressionHumansStress Disorders, Post-TraumaticCancer survivorLifestyleMeta-analysisPsychosocial outcomesSystematic reviewTertiary prevention

Identifiers

PMID39516326
PMCPMC13144231

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.