Evidence map›Paper›PMID 39516281›Full record

ArticleThe EMBO journal2024

Structural basis of 3'-tRNA maturation by the human mitochondrial RNase Z complex.

Genís Valentín Gesé, B Martin Hällberg

Abstract read
In one paragraph

Article in The EMBO journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. OsRNase ZPlant communications · 2026
    Article
  2. Review
  3. The regulation, function and disease relevance of cytoplasmic tRNAs.Nature reviews. Molecular cell biology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Genís Valentín GeséDepartment of Cell and Molecular Biology, Karolinska Institutet, Solna, Sweden.ORCID http://orcid.org/0000-0002-1890-5524
B Martin HällbergDepartment of Cell and Molecular Biology, Karolinska Institutet, Solna, Sweden. Martin.Hallberg@ki.se.ORCID http://orcid.org/0000-0002-6781-0345

Funding

Knut och Alice Wallenbergs Stiftelse (Knut and Alice Wallenberg Foundation) 2017.0080Knut och Alice Wallenbergs Stiftelse (Knut and Alice Wallenberg Foundation) 2018.0080Vetenskapsrådet (VR) 2018-03808Vetenskapsrådet (VR) 2022-02326
6 · The paper itself

Abstract

Maturation of human mitochondrial tRNA is essential for cellular energy production, yet the underlying mechanisms remain only partially understood. Here, we present several cryo-EM structures of the mitochondrial RNase Z complex (ELAC2/SDR5C1/TRMT10C) bound to different maturation states of mitochondrial tRNA

Indexed as

EndoribonucleasesMitochondriaCryoelectron MicroscopyHumansMethyltransferasesMitochondrial DiseasesMitochondrial ProteinsModels, MolecularMutationNeoplasm ProteinsRNA, MitochondrialRNA Processing, Post-TranscriptionalRNA, TransferRNA, Transfer, HisELAC2 protein, humanEndoribonucleasesMethyltransferasesMitochondrial ProteinsNeoplasm ProteinsRNA, MitochondrialRNase ZRNA, TransferRNA, Transfer, HisTRMT10c protein, humanCryo-EMELAC2MitochondriaRNA ProcessingRNase Z

Identifiers

PMID39516281
PMCPMC11649783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.