Evidence map›Paper›PMID 39515581›Full record

ReviewBiological psychiatry. Cognitive neuroscience and neuroimaging2025

ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices.

Saampras Ganesan, Fernando A Barrios, Ishaan Batta, Clemens C C Bauer, Todd S Braver, Judson A Brewer, Kirk Warren Brown, Rael Cahn, Joshua A Cain, Vince D Calhoun and 48 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Introduction to the Special Issue on Cognitive Neuroscience of Mindfulness.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Article
  3. Decoding Mindfulness With Multivariate Predictive Models.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

58 authors.

Saampras GanesanDepartment of Biomedical Engineering, The University of Melbourne, Carlton, Victoria, Australia; Contemplative Studies Centre, Melbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Victoria, Australia; Systems Lab of Neuroscience, Neuropsychiatry and Neuroengineering, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: saamprasg@student.unimelb.edu.au.
Fernando A BarriosUniversidad Nacional Autónoma de México, Instituto de Neurobiolgía, Querétaro, México.
Ishaan BattaCenter for Translational Research in Neuroimaging and Data Science: Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, Georgia.
Clemens C C BauerDepartment of Psychology, Northeastern University, Boston, Massachusetts; Brain and Cognitive Science, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Todd S BraverDepartment of Psychological and Brain Sciences, Washington University, St. Louis, Missouri.
Judson A BrewerDepartment of Behavioral and Social Sciences, Brown University, School of Public Health, Providence, Rhode Island.
Kirk Warren BrownDepartment of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Rael CahnUniversity of Southern California Department of Psychiatry & Behavioral Sciences, Los Angeles, California; University of Southern California Center for Mindfulness Science, Los Angeles, California.
Joshua A CainInstitute for Advanced Consciousness Studies, Santa Monica, California.
Vince D CalhounCenter for Translational Research in Neuroimaging and Data Science: Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, Georgia.
Lei CaoDepartment of Psychiatry and Behavioral Health, The Ohio State University College of Medicine, Columbus, Ohio.
Gaël ChetelatNormandie University, Université de Caen Normandie, INSERM U1237, Neuropresage Team, Cyceron, Caen, France.
Christopher R K ChingImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California.
J David CreswellDesert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System, San Diego, California.
Paulina Clara DagninoComputational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain.
Svend DavangerDivision of Anatomy, Institute of Basic Medical Science, University of Oslo, Oslo, Norway.
Richard J DavidsonPsychology Department and Department of Psychiatry, University of Wisconsin-Madison, Madison, Wisconsin; Center for Healthy Minds, University of Wisconsin-Madison, Madison, Wisconsin.
Gustavo DecoComputational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain; Institució Catalana de la Recerca i Estudis Avançats, Barcelona, Catalonia, Spain.
Janine M DutcherDepartment of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Anira EscrichsComputational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain.
Lisa T EylerDesert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System, San Diego, California; Department of Psychiatry, University of California, San Diego, La Jolla, California.
Negar FaniDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia.
Norman A S FarbDepartment of Psychology, University of Toronto, Mississauga, Ontario, Canada; Department of Psychological Clinical Science, University of Toronto, Scarborough, Ontario, Canada.
Suruchi FialokeNational Resource Center for Value Education in Engineering, Indian Institute of Technology, New Delhi, India.
David M FrescoDepartment of Psychiatry and Institute for Social Research, University of Michigan, Ann Arbor, Michigan.
Rahul GargNational Resource Center for Value Education in Engineering, Indian Institute of Technology, New Delhi, India; Department of Computer Science and Engineering, Indian Institute of Technology, New Delhi, India.
Eric L GarlandCenter on Mindfulness and Integrative Health Intervention Development, University of Utah, Salt Lake City, Utah.
Philippe GoldinBetty Irene Moore School of Nursing, University of California Davis, Sacramento, California.
Danella M HafemanDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Neda JahanshadImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Yoona KangDepartment of Psychology, Rutgers University - Camden, Camden, New Jersey.
Sahib S KhalsaLaureate Institute for Brain Research, Tulsa, Oklahoma; Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California.
Namik KirlicLaureate Institute for Brain Research, Tulsa, Oklahoma.
Sara W LazarDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Antoine LutzEduwell Team, Lyon Neuroscience Research Centre, INSERM U1028, CNRS UMR 5292, Lyon University, Lyon, France; Lyon Neuroscience Research Centre, INSERM U1028, Lyon, France.
Timothy J McDermottDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia.
Giuseppe PagnoniDepartment of Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Camille PiguetPsychiatry Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Ruchika S PrakashDepartment of Psychology, The Ohio State University, Columbus, Ohio.
Hadley RahrigPsychology Department and Department of Psychiatry, University of Wisconsin-Madison, Madison, Wisconsin.
Nicco ReggenteInstitute for Advanced Consciousness Studies, Santa Monica, California.
Luigi F SaccaroPsychiatry Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland; Psychiatry Department, Geneva University Hospital, Geneva, Switzerland.
Matthew D SacchetMeditation Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Greg J SiegleDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yi-Yuan TangCollege of Health Solutions, Arizona State University, Phoenix, Arizona.
Sophia I ThomopoulosImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Paul M ThompsonImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Alyssa TorskeDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Isaac N TrevesBrain and Cognitive Science, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Vaibhav TripathiCenter for Brain Science and Department of Psychology, Harvard University, Cambridge, Massachusetts.
Aki TsuchiyagaitoLaureate Institute for Brain Research, Tulsa, Oklahoma; Oxley College of Health & Natural Sciences, The University of Tulsa, Tulsa, Oklahoma; Research Center for Child Mental Development, Chiba University, Chiba, Japan.
Matthew D TurnerDepartment of Psychiatry and Behavioral Health, The Ohio State University College of Medicine, Columbus, Ohio.
David R VagoDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts.
Sofie ValkMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Institute of Systems Neuroscience, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany; Institute of Neuroscience and Medicine, INM-7, Brain & Behaviour Research Centre Jülich, Jülich, Germany.
Fadel ZeidanDepartment of Anesthesiology, University of California San Diego, La Jolla, California; T. Denny Sanford Institute for Empathy and Compassion, University of California San Diego, La Jolla, California.
Andrew ZaleskyDepartment of Biomedical Engineering, The University of Melbourne, Carlton, Victoria, Australia; Systems Lab of Neuroscience, Neuropsychiatry and Neuroengineering, The University of Melbourne, Parkville, Victoria, Australia.
Jessica A TurnerDepartment of Psychiatry and Behavioral Health, The Ohio State University College of Medicine, Columbus, Ohio.
Anthony P KingDepartment of Psychiatry and Behavioral Health, The Ohio State University College of Medicine, Columbus, Ohio; Department of Psychology, The Ohio State University, Columbus, Ohio; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio. Electronic address: Anthony.King@osumc.edu.

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI SVAREN, JOHN P · 1985 to 2015
$25.2M
The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI Maëlle Camille Marie Gueguen · 2017 to 2026
$23.7M
TRAINING PROGRAM IN EMOTION RESEARCHT32MH018931 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI Richard J Davidson · 1989 to 2026
$11.6M
Training U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1M
Dual Mechanisms of Cognitive ControlR37MH066078 · NIMH · WASHINGTON UNIVERSITY · PI BRAVER, TODD S · 2013 to 2022
$7.2M
Neural Mechanisms of Vibroacoustically Augmented Breath Focused Mindfulness for Dissociative Traumatized PeopleR01AT011267 · NCCIH · EMORY UNIVERSITY · PI FANI, NEGAR, SIEGLE, GREG J · 2021 to 2025
$4.1M
Neural and cognitive changes associated with mindfulness training in older adultsR01AG048351 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI DICKERSON, BRADFORD C, LAZAR, SARA W · 2015 to 2019
$4.0M
Data-driven solutions for temporal, spatial, and spatiotemporal dynamic functional connectivityR01MH123610 · NIMH · GEORGIA STATE UNIVERSITY · PI ADALI, TULAY, CALHOUN, VINCE D · 2021 to 2025
$3.1M
Analgesic and Opioid Sparing Brain Mechanisms of Mindfulness-Oriented Recovery Enhancement for Chronic Low Back PainR01AT011772 · NCCIH · UNIVERSITY OF UTAH · PI Eric Lee Garland, Fadel Zeidan · 2022 to 2026
$3.0M
Global studies into the Genetic Architecture of the Brain's White Matter Network through Harmonized and Coordinated Analyses in the ENIGMA-ConsortiumR01MH134004 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Neda Jahanshad · 2023 to 2026
$2.6M
Global Deep Learning Initiative to Understand Outcomes in Major DepressionR01MH131806 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Roberto Goya-Maldonado, PAUL M THOMPSON · 2023 to 2026
$2.6M
The plasticity of well-being: A research network to define, measure and promote human flourishingU24AT011289 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2021 to 2024
$2.4M
NCCIH NIH HHS R01 AT006344NCCIH NIH HHS R01 AT011267NCCIH NIH HHS R01 AT011772NCCIH NIH HHS U24 AT011289NIA NIH HHS R01 AG048351NIA NIH HHS R01 AG054427NIBIB NIH HHS U54 EB020403NICHD NIH HHS P30 HD003352NIGMS NIH HHS P20 GM121312NIMH NIH HHS F32 MH134631NIMH NIH HHS K23 MH112852NIMH NIH HHS R01 MH120299NIMH NIH HHS R01 MH123610NIMH NIH HHS R01 MH131806NIMH NIH HHS R01 MH134004NIMH NIH HHS R37 MH066078NIMH NIH HHS T32 MH018931
6 · The paper itself

Abstract

Meditation is a family of ancient and contemporary contemplative mind-body practices that can modulate psychological processes, awareness, and mental states. Over the last 40 years, clinical science has manualized meditation practices and designed various meditation interventions that have shown therapeutic efficacy for disorders including depression, pain, addiction, and anxiety. Over the past decade, neuroimaging has been used to examine the neuroscientific basis of meditation practices, effects, states, and outcomes for clinical and nonclinical populations. However, the generalizability and replicability of current neuroscientific models of meditation have not yet been established, because they are largely based on small datasets entrenched with heterogeneity along several domains of meditation (e.g., practice types, meditation experience, clinical disorder targeted), experimental design, and neuroimaging methods (e.g., preprocessing, analysis, task-based, resting-state, structural magnetic resonance imaging). These limitations have precluded a nuanced and rigorous neuroscientific phenotyping of meditation practices and their potential benefits. Here, we present ENIGMA (Enhancing Neuro Imaging Genetics through Meta Analysis)-Meditation, the first worldwide collaborative consortium for neuroscientific investigations of meditation practices. ENIGMA-Meditation will enable systematic meta- and mega-analyses of globally distributed neuroimaging datasets of meditation using shared, standardized neuroimaging methods and tools to improve statistical power and generalizability. Through this powerful collaborative framework, existing neuroscientific accounts of meditation practices can be extended to generate novel and rigorous neuroscientific insights that account for multidomain heterogeneity. ENIGMA-Meditation will inform neuroscientific mechanisms that underlie therapeutic action of meditation practices on psychological and cognitive attributes, thereby advancing the field of meditation and contemplative neuroscience.

Indexed as

BrainMeditationNeuroimagingHumansConsortiumENIGMAMagnetic resonance imaging (MRI)MeditationMindfulnessNeuroimaging

Identifiers

PMID39515581
PMCPMC11975497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.