Evidence map›Paper›PMID 39515142›Full record

ArticleJournal of hazardous materials2024

Toxicity of microplastic fibers containing azobenzene disperse dyes to human lung epithelial cells cultured at an air-liquid interface.

Amber O'Connor, Anna Villalobos Santeli, Sripriya Nannu Shankar, Amin Shirkhani, Tracie R Baker, Chang-Yu Wu, Borna Mehrad, P Lee Ferguson, Tara Sabo-Attwood

Abstract read
In one paragraph

Article in Journal of hazardous materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amber O'ConnorDepartment of Environmental & Global Health, University of Florida, Gainesville, FL, USA.
Anna Villalobos SanteliDepartment of Civil and Environmental Engineering, Duke University, Durham, USA.
Sripriya Nannu ShankarDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, FL, USA; Department of Environmental and Public Health Sciences, University of Cincinnati, OH, USA.
Amin ShirkhaniDepartment of Chemical, Environmental and Materials Engineering, University of Miami, FL, USA.
Tracie R BakerDepartment of Environmental & Global Health, University of Florida, Gainesville, FL, USA.
Chang-Yu WuDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, FL, USA; Department of Chemical, Environmental and Materials Engineering, University of Miami, FL, USA.
Borna MehradDepartment of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, Gainesville 32610, FL, USA.
P Lee FergusonDepartment of Civil and Environmental Engineering, Duke University, Durham, USA.
Tara Sabo-AttwoodDepartment of Environmental & Global Health, University of Florida, Gainesville, FL, USA; Department of Environmental Health Sciences, University of South Carolina, Columbia, SC, USA. Electronic address: saboattw@mailbox.sc.edu.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Multiscale modeling of the role of heme during invasive pulmonary aspergillosisR01AI135128 · NIAID · UNIVERSITY OF FLORIDA · PI REINHARD LAUBENBACHER, Borna Mehrad · 2018 to 2026
$4.9M
Together: Transforming and Translating Discovery to Improve HealthTL1TR001428 · NCATS · UNIVERSITY OF FLORIDA · PI MCCORMACK, WAYNE T. · 2015 to 2023
$3.9M
15/24- Healthy Brain and Child Development National ConsortiumU01DA055358 · NIDA · UNIVERSITY OF FLORIDA · PI GURKA, KELLY K., SCOTT, LISA S. · 2021 to 2023
$3.7M
Atmospheric transformation of harmful cyanobacterial algae and novel mechanisms of pulmonary toxicityR21ES036635 · NIEHS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SABO-ATTWOOD, TARA L · 2024 to 2025
$426k
Assessing the Pulmonary Toxicity of Microplastic Fibers Complexed with Azo DyesR21ES034098 · NIEHS · UNIVERSITY OF FLORIDA · PI MEHRAD, BORNA · 2023 to 2024
$416k
NCATS NIH HHS TL1 TR001428NCATS NIH HHS UL1 TR001427NIAID NIH HHS R01 AI135128NIDA NIH HHS U01 DA055358NIEHS NIH HHS R21 ES034098NIEHS NIH HHS R21 ES036635
6 · The paper itself

Abstract

There is growing concern surrounding the human health effects following inhalation exposure to microplastic fibers (MPFs). MPFs can harbor chemical additives, such as azobenzene disperse dyes (ADDs), that may contribute to their toxicity. The goal of this study was to determine the acute biological effects of dyed polyethylene terephthalate MPFs to fully differentiated normal human bronchial epithelial (NHBE) cells cultured at an air-liquid interface. Cells were exposed to 2000 undyed MPFs (84.80 µg/cm

Indexed as

Azo CompoundsCell SurvivalColoring AgentsEpithelial CellsCell LineCells, CulturedCytochrome P-450 CYP1A1HumansLungMicroplasticsazobenzeneAzo CompoundsColoring AgentsCYP1A1 protein, humanCytochrome P-450 CYP1A1MicroplasticsChemical AdditivesDisperse Violet 93Polyethylene TerephthalateRespiratory ToxicityXenobiotic Metabolism

Identifiers

PMID39515142
PMCPMC11698483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.