Trial reportAmerican journal of respiratory and critical care medicine2025
Humidified Noninvasive Ventilation versus High-Flow Therapy to Prevent Reintubation in Patients with Obesity: A Randomized Clinical Trial.
Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- High-Flow Nasal Cannula Versus Noninvasive Ventilation for Prevention of Reintubation in High-Risk Critically Ill Patients (HIGH-FLOW OXY): An Informative Systematic Review and Meta-Analysis.Critical care explorations · 2026Pooled it
- The efficacy of high-flow nasal cannula versus non-invasive mechanical ventilation in preventing reintubation in patients at high risk of extubation failure: systematic review and meta-analysis with trial sequential analysis.Critical care science · 2026Pooled it
- Physiological Effects of High-Flow Nasal Oxygen Compared With Conventional Oxygen Therapy: A Randomized Trial in Postextubation Patients.Critical care medicine · 2026Trial
- Noninvasive ventilation in postoperative critically ill patients with morbid obesity: secondary analysis of the EXTUBOBESE multicentre randomised clinical trial.British journal of anaesthesia · 2025Trial
- Acute respiratory distress syndrome in patients with obesity.Intensive care medicine · 2026Article
- Prophylactic NIV after extubation in non-hypercapnic high-risk patients: moving beyond convenience toward clinical benefit.Intensive care medicine · 2026Article
- High-flow nasal cannula oxygen during breaks from noninvasive ventilation after extubation: an observational study.Intensive care medicine · 2026Observational
- Author Response: High Flow Nasal Cannula Over Non-invasive Ventilation in Preventing Reintubation: Signal Bias or Both?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Mechanical ventilation for ICU patient with obesity: current best practices and future directions.Intensive care medicine · 2026Review
- Prophylactic noninvasive ventilation after extubation in high-risk patients without hypercapnia.Intensive care medicine · 2026Article
- To: The efficacy of high-flow nasal cannula versus non-invasive mechanical ventilation in preventing reintubation in patients at high risk of extubation failure: systematic review and meta-analysis with trial sequential analysis.Critical care science · 2026Article
- A clinical guide to non-invasive respiratory support in acute respiratory failure: ventilation settings, technical optimization and clinical indications.Critical care (London, England) · 2025Review
- Does obesity impact on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study.Annals of intensive care · 2025Article
- Reply to Yang: Different Ventilation Methods and Reintubation in Obese Patients.American journal of respiratory and critical care medicine · 2025Article
- Different Ventilation Methods and Reintubation in Obese Patients.American journal of respiratory and critical care medicine · 2025Article
- A retrospective study to predict failure of high-flow oxygen therapy for acute hypoxic respiratory failure.International journal of emergency medicine · 2025Article
- Prophylactic Noninvasive Ventilation after Extubation of Obese Patients.American journal of respiratory and critical care medicine · 2025Article
- Best clinical model predicting extubation failure: a diagnostic accuracy post hoc analysis.Intensive care medicine · 2025Article
- Noninvasive respiratory support following extubation in critically ill adults with obesity: a systematic review and network meta-analysis.EClinicalMedicine · 2025Article
- High-flow Nasal Cannula Oxygen vs Non-invasive Ventilation with Passive Humidification: Are We Comparing Like with Like?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care MedicineArticle
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
39514845What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.