Evidence map›Paper›PMID 39514011›Full record

ArticleMikrochimica acta2024

Highly specific detection of ROR1 cancer biomarker with bipolar electrochemiluminescence.

Seyed Mohammad Reza Mortazavi, Morteza Hosseini, Guobao Xu, Hossein Naderi-Manesh, Mohammad Reza Ganjali

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seyed Mohammad Reza MortazaviNanobiosensors Lab, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran.
Morteza HosseiniNanobiosensors Lab, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran. hosseini_m@ut.ac.ir.
Guobao XuState Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
Hossein Naderi-ManeshDepartment of Biophysics, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran.
Mohammad Reza GanjaliCenter of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An electrochemiluminescence (ECL) detection system is presented integrated with a bipolar electrode system for sensitive cancer diagnosis. In order to achieve the highest electrical conductivity and redox-active surface area, MXene was chosen as the material for the bipolar electrode. As part of the detection process, the anodic pole of the bipolar electrode was modified with the receptor tyrosine kinase like orphan receptor 1 (ROR1) antibody, followed by an immunoassay using the ROR1 antibody-modified Ag triangle that was identified as significantly enhancing ECL. We measured the ECL of luminol using the anode pole of BPE as an analytical signal in the presence of H

Indexed as

Biomarkers, TumorElectrochemical TechniquesLuminescent MeasurementsReceptor Tyrosine Kinase-like Orphan ReceptorsAntibodies, ImmobilizedBiosensing TechniquesElectrodesHumansImmunoassayLimit of DetectionLuminolNeoplasmsAntibodies, ImmobilizedBiomarkers, TumorLuminolReceptor Tyrosine Kinase-like Orphan ReceptorsROR1 protein, humanBipolar electrochemistryCancer diagnosisElectrochemiluminescenceImmunoassayMXene

Identifiers

PMID39514011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.