Evidence map›Paper›PMID 39513866›Full record

ArticleCells2024

Su(H) Modulates Enhancer Transcriptional Bursting in Prelude to Gastrulation.

Kelli D Fenelon, Priyanshi Borad, Biraaj Rout, Parisa Boodaghi Malidarreh, Mohammad Sadegh Nasr, Jacob M Luber, Theodora Koromila

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kelli D FenelonDepartment of Biology, University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0002-1294-9200
Priyanshi BoradDepartment of Biology, University of Texas at Arlington, Arlington, TX 76010, USA.
Biraaj RoutDepartment of Computer Science, University of Texas at Arlington, Arlington, TX 76010, USA.
Parisa Boodaghi MalidarrehDepartment of Computer Science, University of Texas at Arlington, Arlington, TX 76010, USA.
Mohammad Sadegh NasrDepartment of Computer Science, University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0001-9675-5640
Jacob M LuberDepartment of Computer Science, University of Texas at Arlington, Arlington, TX 76010, USA.
Theodora KoromilaDepartment of Biology, University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0001-5504-1369

Funding

UTA STARS 123456
6 · The paper itself

Abstract

Transcriptional regulation, orchestrated by the interplay between transcription factors (TFs) and enhancers, governs gene expression dynamics crucial for cellular processes. While gross qualitative fluctuations in transcription factor-dependent gene expression patterning have a long history of characterization, the roles of these factors in the nuclei retaining expression in the presence or absence of these factors are now observable using modern techniques. Our study investigates the impact of Suppressor of Hairless (Su(H)), a broadly expressed transcription factor, on enhancer-driven transcriptional modulation using

Indexed as

Drosophila melanogasterDrosophila ProteinsEnhancer Elements, GeneticGastrulationGene Expression Regulation, DevelopmentalRepressor ProteinsAnimalsEmbryo, NonmammalianTranscription FactorsTranscription, GeneticDrosophila ProteinsRepressor ProteinsSu(H) protein, DrosophilaTranscription Factorsembryogenesisgene expression dynamicsNotch/Hairless signalingsog enhancerSu(H)transcriptional bursting

Identifiers

PMID39513866
PMCPMC11545809

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.