Evidence map›Paper›PMID 39513556›Full record

ArticleJournal of veterinary internal medicine

Serum electrolyte abnormalities in cats with chronic inflammatory enteropathy.

Iona Baker, Romy Heilmann, Ramona Knoll, Berenice Schneider, Yuvani Bandara, Simon Priestnall, Aarti Kathrani

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iona BakerRoyal Veterinary College, University of London, London AL97TA, United Kingdom.
Romy HeilmannUniversity of Leipzig, Leipzig, Sachsen, Germany.ORCID https://orcid.org/0000-0003-3485-5157
Ramona KnollUniversity of Leipzig, Leipzig, Sachsen, Germany.
Berenice SchneiderUniversity of Leipzig, Leipzig, Sachsen, Germany.
Yuvani BandaraColorado State University, Fort Collins, Colorado, USA.
Simon PriestnallRoyal Veterinary College, University of London, London AL97TA, United Kingdom.
Aarti KathraniRoyal Veterinary College, University of London, London AL97TA, United Kingdom.ORCID https://orcid.org/0000-0001-5569-794X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited information is available on electrolyte abnormalities in cats with chronic inflammatory enteropathy (CIE). HYPOTHESIS/

objectivesReport the prevalence of electrolyte abnormalities in cats with CIE compared to other gastrointestinal disorders, and determine their association with disease and outcome variables in cats with CIE. ANIMALS: Three hundred twenty-eight client-owned cats from 2 referral hospitals: CIE (132), alimentary small cell lymphoma (29), acute gastroenteritis (48), and healthy controls (119).

methodsRetrospective study comparing serum electrolyte concentrations at time of diagnosis among the 4 groups of cats, and associations with clinical signs, intestinal mucosal fibrosis scores, treatment subclassification and outcome in CIE.

resultsCats with CIE had lower sodium and higher potassium concentrations and lower sodium: potassium ratios compared with healthy cats (P < .001, P = .01, and P < .001, respectively). Cats with CIE and a duodenal mucosal fibrosis score of 2 had lower sodium and lower total calcium concentrations compared with cats that had a score of 0 (P = .02 and P = .01). Cats with CIE and a colonic mucosal fibrosis score of 1 had higher potassium concentrations and lower sodium: potassium ratios compared with cats that had a score of 0 (P = .03 and P = .01). Cats with CIE that died as a result of their disease had higher potassium concentrations and lower sodium: potassium ratios compared to cats that were alive (P = .02 and P = .01). CONCLUSIONS AND CLINICAL IMPORTANCE: Electrolyte abnormalities occur with CIE and, in particular, in cats with higher fibrosis scores and worse outcomes. Further research should aim to determine the pathogenesis of these findings and identify novel therapeutic targets for cats with CIE.

Indexed as

Cat DiseasesAnimalsCatsChronic DiseaseElectrolytesFemaleInflammatory Bowel DiseasesMalePotassiumRetrospective StudiesSodiumWater-Electrolyte ImbalanceElectrolytesPotassiumSodiumdiarrheafelineintestinepotassiumsodiumvomiting

Identifiers

PMID39513556
PMCPMC11586583

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.