ArticleJournal of animal science2024
Dietary Zanthoxylum bungeanum leaf powder improves growth performance and antioxidant capacity via Nrf2/HO-1 signaling pathway in broilers.
Article in Journal of animal science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- DietaryFoods (Basel, Switzerland) · 2026Article
- DietaryAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Effects ofAnimals : an open access journal from MDPI · 2026Article
- Effects of Dietary Supplementation with FermentedFoods (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study focused on the effects of dietary Zanthoxylum bungeanum leaves (ZBL) powder on the growth performance and antioxidant capacity via the Nrf2/HO-1 signaling pathway in broilers. The experiment adopted a single-factor completely random design, and 440 healthy 1-d-old Arbor Acres broiler chicks were randomly divided into 4 groups: the control group (CON) was fed a corn-soybean meal-based diet, the CZ1 group was fed a basic diet with 1% ZBL powder, the CZ2 group fed a basic diet with 2% ZBL powder, and the CZ3 group fed a basic diet with 3% ZBL powder. The experiment was divided into the starter period (1 to 21 d) and the grower period (22 to 42 d). There were 5 replicates per group in the starter period, with 22 chickens per replicate. The same grouping as in the starter period was used in the grower period, with 20 chickens per replicate. The results showed that the addition of ZBL powder to the diet had no adverse effects on the growth performance and morphological structure of the intestine of broiler chickens in the CZ1 and CZ2 groups (P > 0.05). Compared with the control group, the diet with 1% and 2% ZBL powder significantly increased the antioxidant indicators such as CAT, T-AOC, and T-SOD in the serum and liver tissue of broiler chickens, it upregulated the related gene expression of nuclear factor erythroid derived-2/heme oxygenase-1 (Nrf2/HO-1) signaling pathway such as Nrf2, NQO1, HO-1, SOD1, and CAT in the jejunal mucosa and enhanced the expression of ZO-1 and OCLN genes in the jejunal mucosa (P < 0.05). In conclusion, dietary supplementation with 1% and 2% of ZBL powder in the daily diet can enhance the body's antioxidant capacity by elevating antioxidant levels in both serum and liver, upregulating the expression of genes associated with the Nrf2/HO-1 signaling pathway in the jejunal mucosa, and helps maintain the integrity of the intestinal mucosal barrier. The optimal addition level of ZBL powder in the diet was determined by quadratic regression analysis to be 1.36% to 1.60% during days 1 to 21 and 1.14% to 1.50% during days 22 to 42.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.