Evidence map›Paper›PMID 39513151›Full record

ArticleFrontiers in nuclear medicine2024

A novel method in myocardial injury risk stratification using intravenous fat emulsion as sole rapid preparation for unfasted patients to suppress myocardial 18F-fluorodeoxyglucose uptake for optimal cardiac PET imaging: a proof-of-concept randomized-crossover trial.

Michael H-G Li, Raef R Boktor, Christopher Rowe, Laurence Weinberg, Bernhard Riedel

Abstract read
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Article in Frontiers in nuclear medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael H-G LiDepartment of Anaesthesia, Austin Health, Heidelberg, VIC, Australia.
Raef R BoktorDepartment of Molecular Imaging and Therapy, Austin Health, Heidelberg, VIC, Australia.
Christopher RoweDepartment of Molecular Imaging and Therapy, Austin Health, Heidelberg, VIC, Australia.
Laurence WeinbergDepartment of Anaesthesia, Austin Health, Heidelberg, VIC, Australia.
Bernhard RiedelDepartment of Anaesthesia, Perioperative and Pain Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Optimal imaging of ischemic or inflammed myocardium via Methods: We conducted an ethics-approved, single-blind, prospective randomized crossover trial of 10 healthy volunteers from January 2020 to June 2021. Participants were unfasted and rendered hyperglycemic before being administered either high dose intravenous lipid emulsion-1.5 ml kg of 20% lipid emulsion, followed by 15 ml/kg/hr for 30mins-or saline prior to Results: The study population age was 44.5 years [IQR 32.5-56.5], with 50% male and a median BMI of 22.75 [IQR 25.0-28.5] kg/m Conclusions: Intravenous lipid emulsion suppresses background metabolic uptake of

Indexed as

18F-FDG18F-fluorodeoxyglucosecardiac imaging techniquesfat emulsionhealthy volunteersintravenousPETpositron emission tomography computed tomography

Identifiers

PMID39513151
PMCPMC11541950

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.