ArticleCanadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD2024
Comparison of oncostatin M cytokine levels in saliva and serum in periodontitis: a clinicobiochemical study.
Article in Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
2 authors.
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Abstract
Background: Oncostatin M (OSM), a 28 kDa glycoprotein 130 pleiotropic cytokine belonging to the interleukin-6 (IL-6) family, is mainly produced by neutrophils, activated T cells, monocytes, and macrophages. In response to tissue injury, it may stimulate the production of IL-6 alone or act synergistically with IL-6 or TNF-α contributing to the inflammatory cycle. Periodontitis is an inflammatory disease resulting from a dysbiotic bacterial community, which has a strong association with increased OSM production. Objectives: To investigate and compare the levels of salivary and serum OSM in healthy subjects and subjects with periodontitis. Materials and methods: Eighty-eight (88) individuals between the ages of 25 and 60 years were divided into 2 groups of 44: a periodontally healthy group (Group A) and a periodontitis group (Group B) based on clinical examination and radiographic analysis. Evaluation of salivary and serum OSM by enzyme-linked immunosorbent assay (ELISA) was performed in both groups. Results: There was a significant difference in OSM levels between Groups A and B ( Conclusion: The expression of cytokine OSM may play a potential role in the immunopathogenesis of periodontitis, suggesting a role as an inflammatory diagnostic marker.
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Identifiers
39513097PMC11539946What OpenQuestion holds
Registered trials
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