Evidence map›Paper›PMID 39513072›Full record

ArticleJMA journal2024

Does the Number of Turns during Sleep Have Utility in the Early Detection of Parkinson's Disease and Its Related Disorders?

Tokuharu Tanaka, Hidenori Onishi, Masaki Kiyono, Yuki Miyazaki, Azusa Tanaka, Akihiko Tanizawa, Tadanori Hamano, Hiroyuki Hayashi, Koji Kobayashi, Osamu Yamamura

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Article in JMA journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tokuharu TanakaDepartment of Family and Emergency Medicine, University of Fukui Hospital, Fukui, Japan.
Hidenori OnishiRegional Medicine Promotion Course, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Masaki KiyonoBiomedical Imaging Research Center, University of Fukui, Fukui, Japan.
Yuki MiyazakiBiomedical Imaging Research Center, University of Fukui, Fukui, Japan.
Azusa TanakaRegional Medicine Promotion Course, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Akihiko TanizawaSugita Genpaku Memorial Obama Municipal Hospital, Fukui, Japan.
Tadanori HamanoDepartment of Neurology, University of Fukui Hospital, Fukui, Japan.
Hiroyuki HayashiDepartment of Family and Emergency Medicine, University of Fukui Hospital, Fukui, Japan.
Koji KobayashiDepartment of Medical Technology, Kitasato Junior College of Health and Hygienic Sciences, Niigata, Japan.
Osamu YamamuraRegional Medicine Promotion Course, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with Parkinson's disease (PD) and its related disorders exhibit decreased sleep activity. However, the factors associated with this decreased sleep activity remain unknown. Thus, we aimed to explore the factors associated with sleep activity in patients with PD and its related disorders. Methods: This study included 33 patients with PD and its related disorders and 57 healthy participants who visited our outpatient clinics between November 2018 and March 2020. We evaluated the patients' muscle masses and measured the number of times they turned during sleep. The limb skeletal muscle index was utilized to evaluate the loss of muscle mass. This study was registered in the UMIN Clinical Trials Registry (Clinical Trials Registry number: UMIN000052436). Results: Age, maximal grip strength, presarcopenia, phase angle (legs), history of hypertension, diabetes mellitus, dyslipidemia, orthopedic diseases, and the number of turns during sleep were associated with PD and its related disorders. The number of turns was independently associated with PD and its related disorders. Receiver operating characteristic curve analysis revealed that the cutoff value for the number of turns was 6 (area under the curve, 0.986; sensitivity, 93.9%; specificity, 96.5%). The cutoff numbers of turns for men and women were 9 and 6, respectively (area under the curve, 1.0 and 0.981; sensitivity, 100% and 94.7%; specificity, 100% and 95.2%; respectively). Conclusions: The number of turns during sleep is significantly associated with PD and its related disorders and may decrease before patients present with sarcopenia. In addition, PD and its related disorders may coexist in men who turn less than nine times during sleep.

Indexed as

number of turnsParkinson’s diseasephase anglesex-specific differencesleep activity

Identifiers

PMID39513072
PMCPMC11543352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.