ReviewCureus2024
Epigenetics and Asthma: A Systematic Review.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Epigenetics in asthma: implications for treatable traits.Frontiers in allergy · 2026Review
- The mechanism and clinical significance of FKBP5 gene DNA methylation in various psychiatric, metabolic and tumor-related diseases.Frontiers in genetics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a chronic respiratory condition characterized by the narrowing of the airways, causing difficulty in breathing. Its heritability has long been an area of research, and the study of genetics alone has not been sufficient in the explanation of both its heritability and susceptibility. The study of epigenetics, which is defined as "the study of heritable changes in gene expression that do not involve changes to the underlying DNA sequence," can be used to explain the heritability and susceptibility of asthma. These epigenetic alterations to our DNA are influenced by environmental factors which are already known as risk factors for asthma; these include factors such as diet, smoking, and air pollution. The epigenetic mechanisms work by altering gene transcription and therefore determine whether specific genes are expressed, such mechanisms include DNA methylation and histone acetylation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.