Evidence map›Paper›PMID 39512869›Full record

ReviewEuropean urology open science2024

Efficacy and Safety of Semirigid Ureteroscopy Combined with Holmium:yttrium-aluminum-garnet Laser Lithotripsy for the Treatment of Proximal Ureteral Calculi: A Single-arm Meta-analysis.

Zhilong Li, Xiaoyu Tang, Shaojie Wu, Shaoxi Liu, Xiaolong Wang, Ziqi He, Du Wang, XingHuan Wang, Sheng Li

Abstract readReview
In one paragraph

Review in European urology open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhilong LiDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xiaoyu TangDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shaojie WuDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shaoxi LiuDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xiaolong WangDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ziqi HeDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Du WangThe Institute of Technological Sciences, Wuhan University, Wuhan, China.
XingHuan WangDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Sheng LiDepartment of Urology, Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Ureteral stones are currently treated with holmium:yttrium-aluminum-garnet (Ho:YAG) laser lithotripsy using rigid and flexible ureteroscopes. This study aims to evaluate the efficacy and safety of semirigid ureteroscopy combined with Ho:YAG laser lithotripsy for treating proximal ureteral stones in real-world studies. Methods: The PubMed, Embase, and Web of Science databases were searched systematically to retrieve all relevant studies up to April 2024. A meta-analysis of the retrieved studies was performed using Stata 14.0 software and expressed as rate, mean difference, and 95% confidence interval (CI). The main outcomes of this meta-analysis were stone-free rate (SFR) and perioperative outcomes including operation time, hospital stay, postoperative ureteral stent placement, auxiliary procedures, and intra- or postoperative complications. Key findings and limitations: A total of 24 studies were included in this study, including 2058 patients with proximal ureteral stones. According to the results of the combined analysis, the SFR of semirigid ureteroscopy combined with Ho:YAG laser lithotripsy for the treatment of proximal ureteral stones was 78% (95% CI [75%, 82%]), operation time was 51.03 min (95% CI [43.5, 58.56]), hospital stay was 1.62 d (95% CI [1.54, 1.70]), auxiliary procedure rate was 20% (95% CI [15%, 25%]), and postoperative complication rate was 16% (95% CI [12%, 22%]). Conclusions and clinical implications: The results of this study show that semirigid ureteroscopic Ho:YAG laser lithotripsy is a commonly used treatment for proximal ureteral calculi, but its efficacy and safety need to be improved further, and its efficacy is not related to the diameter of the endoscope. Patient summary: This study showed that Ho:YAG laser lithotripsy with semirigid ureteroscopes is commonly used for treating ureteral stones. However, its efficacy and safety need to be improved further, and future research should focus on these.

Indexed as

Holmium:yttrium-aluminum-garnetMeta-analysisProximal ureteral stonesSystematic reviewUreteroscopic lithotripsy

Identifiers

PMID39512869
PMCPMC11541942

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.