ArticleObesity science & practice2024
Results of a pilot sequential multiple assignment randomized trial using counseling to augment a digital weight loss program.
Article in Obesity science & practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05929469 (PATH to Health), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PATH to Health: An Exploration of Digital Behavioral Weight Loss Approaches
Who cites it
2 citing papers in PubMed.
- Precision in progress: a scoping review of SMART designs in adaptive behavioral interventions for individuals with a chronic physical and/or mental illness.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2026Article
- Results of a pilot sequential multiple assignment randomized trial using counseling to augment a digital weight loss program.Obesity science & practice · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Objective: Adaptive interventions may improve the potency and scalability of behavioral weight loss interventions, but the treatments-or treatment combinations-that should be offered are unknown. A two-stage pilot sequential multiple assignment randomized trial was used to test the timing and dose of human support added to a core digital weight loss program. Methods: In stage 1, 99 adults with overweight/obesity were randomized at baseline to a kick-off with or without additional human support. In stage 2, "early non-responders" who had not achieved a 2% weight loss were re-randomized after 4 weeks to either biweekly counseling (120 min over 8 weeks) or a one-time check-in (30 min) with a dietitian. "Early responders" continued with the mHealth program alone. Feasibility and acceptability were assessed against pre-specified criteria. Preliminary outcomes (weight loss, self-monitoring and behavioral goal adherence) were explored. Results: The study met all feasibility and acceptability criteria. The rate of early response was 52.5%. Mean (SE) 3-month percent weight losses were significantly greater in early responders (-6.63% (0.72)) than non-responders (-1.70% (0.43), Conclusions: Identifying early responders may help optimize weight loss interventions, but more research is needed on rescue treatments for early non-responders. Trial Registration: ClinicalTrial.gov, NCT05929469.
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Registered trials
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