Evidence map›Paper›PMID 39512595›Full record

ArticleACS sustainable chemistry & engineering2024

Optimization of Biocatalytic Rhododendrol Production from Biogenic Rhododendrol Glycosides.

Emerik Leaković, Karsten Siems, Michel Feussi Tala, Antonia Habazin, Zvjezdana Findrik Blažević, Ana Vrsalović Presečki

Abstract read
In one paragraph

Article in ACS sustainable chemistry & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emerik LeakovićUniversity of Zagreb Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, HR-10000 Zagreb, Croatia.
Karsten SiemsAnalytiCon Discovery GmbH, Hermannswerder 17, 14473 Potsdam, Germany.
Michel Feussi TalaAnalytiCon Discovery GmbH, Hermannswerder 17, 14473 Potsdam, Germany.
Antonia HabazinUniversity of Zagreb Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, HR-10000 Zagreb, Croatia.
Zvjezdana Findrik BlaževićUniversity of Zagreb Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, HR-10000 Zagreb, Croatia.
Ana Vrsalović PresečkiUniversity of Zagreb Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, HR-10000 Zagreb, Croatia.ORCID https://orcid.org/0000-0002-0247-4483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An enzyme-catalyzed synthesis of rhododendrol, an intermediate in the production of raspberry ketone, was investigated. The approach involves the enzymatic hydrolysis of rhododendrol glycosides into rhododendrol and a glycosidic residue. Rhododendrol glycosides, which are naturally derived from the inner bark of birch trees-a renewable resource-vary considerably in composition depending on the origin of the plants. In this study, mixtures of betuloside and apiosylrhododendrin from natural resources were used in different proportions. An in-depth study was conducted to assess the feasibility of the process. A mathematical model was developed based on studies of the kinetics and operational stability of the enzyme. The model for betuloside hydrolysis catalyzed by β-glucosidase was validated in batch, repetitive batch, and ultrafiltration membrane reactors. The highest productivity, ranging from 83.9 to 94.5 g L

Identifiers

PMID39512595
PMCPMC11539071

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.