ArticlePain reports2024
Pain and small fiber pathology in men with fibromyalgia syndrome.
Article in Pain reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Fibromyalgia syndrome-Is the designation as a disorder of women a misinterpretation?]Schmerz (Berlin, Germany) · 2026Pooled it
- Fibromyalgia in men: beyond invisibility-a biopsychosocial and clinical perspective in rheumatology.Clinical rheumatology · 2026Review
- [Fibromyalgia syndrome].Innere Medizin (Heidelberg, Germany) · 2026Review
- Evaluating skin biopsy findings in fibromyalgia: a systematic review.Reumatologia · 2026Review
- Small Fibre Pathology in Fibromyalgia: A review.Pain and therapy · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Small fiber pathology may be involved in the pathophysiology of pain in women with fibromyalgia syndrome (FMS). Objectives: This prospective single-center case-control study provides detailed pain phenotyping and small fiber pathology data in a cohort of men with FMS on a morphological and functional level. Methods: Forty-two men with FMS underwent a comprehensive pain-related interview and neurological examination, a questionnaire and neurophysiological assessment, and specialized small fiber tests: skin punch biopsy, quantitative sensory testing including C-tactile afferents, and corneal confocal microscopy. Data were compared with those of healthy male controls. Results: Men with FMS reported generalized and permanent pain with additional pain attacks and a mostly pressing pain character. Intraepidermal nerve fiber density was reduced at ≥1 biopsy site in 35 of 42 (83%) men with FMS (controls: 32/65, 49%). Compared with male controls, men with FMS had elevated cold ( Conclusion: We show a distinct pain phenotype and small nerve fiber dysfunction and pathology in male patients with FMS. These findings may have implications for the diagnosis and management of men with FMS.
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Registered trials
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