Evidence map›Paper›PMID 39512582›Full record

ArticleDental research journal2024

Cytotoxicity of dental ceramic materials on human gingival fibroblasts.

Omid Savabi, Farahnaz Nejatidanesh, Morteza Sharifi, Mohammadjavad Shirani, Alireza Valanezhad, Ikuya Watanabe, Batool Hashemi Beni, Mohammad Khodaei

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Dental research journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Omid SavabiDental Research Center, Department of Prosthodontics, Dental Research Institute, Isfahan University of Medical Sciences, Golpayegan, Isfahan, Iran.
Farahnaz NejatidaneshDental Materials Research Center, Department of Prosthodontics, Dental Research Institute, Isfahan University of Medical Sciences, Golpayegan, Isfahan, Iran.
Morteza SharifiDental Materials Research Center, Department of Prosthodontics, Dental Research Institute, Isfahan University of Medical Sciences, Golpayegan, Isfahan, Iran.
Mohammadjavad ShiraniDepartment of Restorative Dentistry, Maurice H. Kornberg School of Dentistry, Temple University, Philadelphia, PA.
Alireza ValanezhadDepartment of Dental and Biomedical Materials Science, Nagasaki University, Nagasaki, Japan.
Ikuya WatanabeDepartment of Dental and Biomedical Materials Science, Nagasaki University, Nagasaki, Japan.
Batool Hashemi BeniDepartment of Anatomical Sciences and Molecular Biology, Dental Research Center, Dental Research Institute, School of Medicine, Isfahan University of Medical Sciences, Golpayegan, Isfahan, Iran.
Mohammad KhodaeiMaterials Engineering Group, Golpayegan College of Engineering, Isfahan University of Technology, Golpayegan, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to evaluate the effect of new computer-aided design/computer-aided manufacturing all-ceramic materials on the viability and adhesion properties of human gingival fibroblasts (HGFs). Materials and Methods: In this experimental study, the proliferation and adhesion potential of the cells were evaluated by seeding the HGF cells on rectangular samples ( Results: The highest percentage of cell viability after 24 h, 72 h, and 168 h cultures was related to ZLS, LDS, and CZr, respectively. The lowest proliferation of fibroblast cells was shown in ZLS compared to other groups. SEM analysis showed that the CZr and LDS groups have better adhesion patterns and morphology. The surface of HyC groups was significantly less rough than other groups. Regarding the water wetting angle (wettability), the TZr and CZr showed significantly larger angles. Conclusion: Within the limitation of this study, it can be concluded that CZr and LDS ceramics had better adhesion patterns and typical morphology. On the other hand, zirconia with a larger wetting angle can reduce the chance of bacteria adhesion to the surface.

Indexed as

Ceramicsdental materials/toxicityfibroblasts/drug effectsgingiva/drug effects

Identifiers

PMID39512582
PMCPMC11542751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.