Evidence map›Paper›PMID 39512532›Full record

ReviewContemporary oncology (Poznan, Poland)2024

Molecular landscape of salivary gland malignancies. What is already known?

Julia Pikul, Anna Rzepakowska

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Contemporary oncology (Poznan, Poland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Julia PikulDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, Warsaw, Poland.
Anna RzepakowskaDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salivary gland carcinomas (SGCs) are highly heterogeneous histopathological entities that arise in either the major or minor salivary glands. Although uncommon, these tumours exhibit considerable aggressiveness, unpredictable progression, and significant mortality. The fifth edition of the World Health Organisation classification of head and neck tumours distinguishes between 24 salivary gland malignancies. This may lead to difficulties in terms of diagnostic accuracy and suitable therapeutic selection. Mucoepidermoid carcinoma occurs most frequently and is characterised by gradual disease progression. Although salivary duct carcinoma, myoepithelial carcinoma, and carcinoma ex pleomorphic adenoma are rarely detected, they contribute to poor patient outcomes. Currently, attempts have been made to establish molecular characterisation of SGCs to improve differential diagnosis and create targeted treatments. This study aimed to summarise current knowledge regarding genetic variations in the most common salivary gland malignancies.

Indexed as

genetic altera-tionsmolecular landscapeNGSsalivary gland carcinoma

Identifiers

PMID39512532
PMCPMC11538980

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.