Evidence map›Paper›PMID 39512466›Full record

ReviewHeliyon2024

Biological functions and molecular mechanisms of LINC01116 in cancer.

Ke Shi, Xue-Ying Wang, Li-De Huang, Qiang Guo, Wei Yuan, Yan Lv, Dan Li

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ke ShiDepartment of Thoracic Surgery, Beilun District People's Hospital of Ningbo, Ningbo City, China.
Xue-Ying WangDepartment of Cardiothoracic Surgery, Taihe Hospital, Hubei Medical University, Shiyan City, China.
Li-De HuangDepartment of Pain management, People's Hospital of Shiyan City, Hubei Medical University, Shiyan City, China.
Qiang GuoDepartment of Cardiothoracic Surgery, Taihe Hospital, Hubei Medical University, Shiyan City, China.
Wei YuanDepartment of Basic Medicine, Hubei University of Medicine, Shiyan City, China.
Yan LvDepartment of Thoracic Surgery, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Dan LiDepartment of Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan City, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

LINC01116, a long non-coding RNA (lncRNA), serves as an important regulator in the progression of cancer cells and has attracted increased attention in biological fields. It is overexpressed in various cancer cells and is significantly correlated with cancer development and poor prognosis in cancer patients. Moreover, LINC01116 regulates the gene expression of various cancers through intricate pathways, such as sponging the microRNAs or other non-genic manners. These signaling pathways greatly affect the cancer's biological functions, including cell growth, migration, invasion, and chemoresistance. Hence, LINC01116 may serve as a prognostic biomarker and therapeutic target for human cancer. This paper summarizes the current evidence regarding the biological functions and molecular mechanisms of LINC01116 in the progression of cancer, providing theoretical references for LINC01116-related cancer treatment in the future.

Indexed as

BiofunctionLINC01116microRNAPrognosis

Identifiers

PMID39512466
PMCPMC11539247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.