Evidence map›Paper›PMID 39512235›Full record

ArticleTherapeutic advances in respiratory disease

Correlation of gastro-esophageal reflux disease with asthma control and quality of life: a cross-sectional study from a low-middle income country.

Nousheen Iqbal, Atiqa Amirali, Ghulam Ullah Lail, Maria Ali Khan, Rabia Sial, Muhammad Irfan

Abstract read
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nousheen IqbalDepartment of Medicine, Jinnah Medical and Dental College, Karachi, Pakistan.ORCID 0000-0001-5026-9874
Atiqa AmiraliJinnah Medical and Dental College, Karachi, Pakistan.
Ghulam Ullah LailDepartment of Medicine, Jinnah Medical and Dental College, Karachi, Pakistan.
Maria Ali KhanEpidemiology and Biostatistics, Imran Idrees Teaching Hospital, Sialkot, Pakistan.
Rabia SialJinnah Medical and Dental College, Karachi, Pakistan.
Muhammad IrfanSection of Pulmonary and Critical Care Medicine, Department of Medicine, Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastro-esophageal reflux disease (GERD) is a chronic disease that coexists with asthma and is often responsible for repeated exacerbations, as well as has a negative impact on the quality of life (QoL). However, from our continent, there is limited data available on the exact prevalence of GERD in asthma and its association with asthma control and QoL.

objectiveTo determine the prevalence of GERD in asthma and see its association with asthma control and QoL.

designA prospective, cross-sectional study was conducted over 8 months from September 2020 to April 2021.

methodsPatients with a confirmed diagnosis of asthma aged 18 years and above were recruited from the outpatient department of pulmonology. Patients' GERD score was calculated using the FSSG SCALE (Frequency Scale for Symptoms of GERD) questionnaire and the Asthma Control Test (ACT) was used to determine asthma control. To assess the QoL, the short form of health survey (SF-36) questionnaire was used. Patients were recruited through a convenience sampling technique.

resultsA total of 190 patients were enrolled, the mean age was 33.7 ± 13.3 years and 55.8% were female. Prevalence of GERD was (136) 71.6%. According to the ACT score, 81 (42.6%) patients had very poorly controlled asthma (mean GERD score of 13.73 ± 7.66), compared to 59 (31.1%) asthmatic patients who had well-controlled asthma (mean GERD score of 11.97 ± 7.39,

conclusionThis study showed a high prevalence of GERD among asthmatic patients with a negative impact on QoL but did not demonstrate a statistically significant relationship between GERD and asthma control.

Indexed as

AsthmaGastroesophageal RefluxQuality of LifeAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceProspective StudiesSurveys and QuestionnairesYoung Adultasthma controlFSSG ScaleGERDhealth-related quality of lifeSF-36

Identifiers

PMID39512235
PMCPMC11544649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.