ArticleThe Journal of international medical research2024
Risk factors for and short-term prognosis of intrauterine infection in preterm infants.
Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Placental pathologic score 1-2 subclinical abnormalities and early neonatal clinical indicators in term infants: a retrospective study.American journal of translational research · 2026Article
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Abstract
objectiveTo identify the risk factors for and short-term prognosis of intrauterine infection (IUI) in preterm infants.
methodsWe retrospectively collected clinical data regarding preterm infants (28
resultsThree hundred thirty (78.1%) of the 422 enrolled neonates showed signs of histologic IUI; 51.8% showed histologic chorioamnionitis alone, and 48.2% showed both histologic chorioamnionitis and funisitis. The independent risk factors identified for IUI were maternal prenatal invasive manipulation, premature rupture of membranes (>18 hours before labor), and prenatal C-reactive protein concentration. The infants with IUI showed higher incidences of respiratory distress syndrome, bronchopulmonary dysplasia, retinopathy of prematurity, and prolonged mechanical ventilation. Low gestational age and low birth weight of preterm infants were significantly associated with a higher incidence of histologic IUI, more severe inflammation, and a higher incidence of complications.
conclusionsHistologic IUI is associated with high complication and mortality rates in preterm infants, as is an increasing severity of inflammation.
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