Evidence map›Paper›PMID 39511675›Full record

ArticleChild and adolescent psychiatry and mental health2024

Clinical profiles and care of transgender children and adolescents who receive specialized consultations: do individuals who are assigned female at birth differ?

Chystelle Lagrange, Nina Verger, Julie Brunelle, Fanny Poirier, Hugues Pellerin, Nicolas Mendes, Gregor Mamou, Nifoular Forno, Laetitia Martinerie, David Cohen and 1 more

Abstract read
In one paragraph

Article in Child and adolescent psychiatry and mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chystelle Lagrange *Service de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Nina Verger *Service de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Julie BrunelleService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Fanny PoirierService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Hugues PellerinService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Nicolas MendesService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Gregor MamouService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Nifoular FornoService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Laetitia MartinerieRéseau Trajectoire Trans d'Ile de France, APHP, Paris, France.
David CohenService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France. david.cohen@aphp.fr.
Agnès CondatService de Psychiatrie de l'Enfant et de l'Adolescent, APHP.SU, Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextClinical data on transgender children and adolescents are scarce, and sample sizes often do not allow for comparisons according to sex assigned at birth. Besides, most gender identity clinics have pointed to a recent switch in favor of an increase in the number of adolescents assigned females at birth (AFAB) over assigned males at birth (AMAB).

methodWe collected data on sociodemographic characteristics, and psychiatric and social vulnerabilities according to sex assigned at birth for all youths who were treated at the French largest gender identity clinic. In addition, management modalities for gender transition were discussed in multidisciplinary concertation meetings.

resultsWe collected data from 239 youths [162(68%) AFAB, 74(32%) AMAB, and 3(1%) intersex; mean age = 14.5(± 3.16) years]. The distribution of age at referral was better explained by two clusters (C1: N = 61, mean age = 11.3 years, with more AMAB; C2: N = 175, mean age = 15.9 years with more AFAB). 215(91%) youths had gender incongruence, with 32% reporting it before puberty. School drop-out, suicidality, depression, and anxiety were common and occurred significantly more often in the AFAB group. 178(74%) youths experienced social transition within the family, and 144(61%) at school [mean age = 15.13(± 2.06) years]. The social transition was more frequent in the AFAB group. Twenty-six (11%) youths received puberty blockers [mean age = 13.87(± 2.31) years], and 105(44%) received gender-affirming hormones [mean age = 16.87(± 1.4) years]. AMABs were more likely to take puberty blockers, and there was no difference in the proportion of AMAB and AFAB taking gender-affirming hormones. Surgical requests (mainly torsoplasty) were very rare.

conclusionAge at referral should be considered when exploring gender incongruence. During adolescence, we found that gender incongruence has substantial social and psychological effects, particularly on AFAB youths, possibly explaining their higher referral rates to specialized centers, as in other specialized clinics around the world.

Indexed as

AdolescenceChildhoodComorbidityGender dysphoriaGender incongruenceTreatment

Identifiers

PMID39511675
PMCPMC11546276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.