Evidence map›Paper›PMID 39511485›Full record

ArticleBMC genomics2024

The genome landscape of the Xinglong buffalo.

Yuan Chai, Shiyuan Li, Hui Wu, Yong Meng, Yujing Fu, Hong Li, Guansheng Wu, Junming Jiang, Taoyu Chen, Yuqing Jiao and 8 more

Abstract read
In one paragraph

Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yuan ChaiHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Shiyuan LiHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Hui WuHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Yong MengHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Yujing FuHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Hong LiHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Guansheng WuHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Junming JiangHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Taoyu ChenHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Yuqing JiaoHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Qiaoling ChenHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Li DuHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Lianbin LiHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Churiga ManHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Si ChenHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China.
Hongyan GaoHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China. gaohongyan@hainanu.edu.cn.
Wenguang ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, People's Republic of China. wenguangzhang@imau.edu.cn.
Fengyang WangHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Hainan University, Haikou, 570228, People's Republic of China. fywang68@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundXinglong buffalo, as an indigenous breed in Hainan province of China, possesses characteristics such as high humidity tolerance, disease resistance and high reproductive capacity. Combined with whole genome sequencing technology, comprehensive investigation can be undertaken to elucidate the genomic characteristics, functions and genetic variation of Xinglong buffalo population.

resultsXinglong buffalo has the highest genetic diversity, lowest runs of homozygosity average length, and fasted decay of linkage disequilibrium in our study population. Phylogenetic tree results revealed that Xinglong buffalo was gathered together with Fuzhong buffalo firstly. The population genetic structure analysis indicates that at K = 3, the Xinglong buffalo for the first time showed a distinct ancestral origin from other water buffalo. Furthermore, compared to different populations, candidate genes displaying significantly distinct patterns of single nucleotide polymorphisms (SNPs) (e.g., RYR2, COX15, PCDH9, DTWD2, FCRL5) distribution have been identified in the Xinglong buffalo.

conclusionsBased on the whole genome sequencing data, this study identified a substantial number of SNPs and assessed the genetic diversity and selection signatures within the Xinglong buffalo population. These results contribute to understanding the genomic characteristics of Xinglong buffalo and their genetic evolutionary status. However, the practical significance of these signatures for genetic enhancement still requires confirmation through additional samples and further experimental validation.

Indexed as

BuffaloesGenomePhylogenyPolymorphism, Single NucleotideAnimalsChinaGenetics, PopulationGenetic VariationGenomicsLinkage DisequilibriumWhole Genome SequencingGenetic diversitySelection signatureWhole-genome sequencingXinglong buffalo

Identifiers

PMID39511485
PMCPMC11542305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.