Evidence map›Paper›PMID 39511481›Full record

ArticleBMC infectious diseases2024

Severe herpes simplex virus - 1 Kaposi varicelliform eruption and SARS-CoV-2 infection in atopic dermatitis treated with dupilumab.

Jiale Zhong, Yujuan Xiao, Yi Liu

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiale ZhongDepartment of Dermatology, The First Affiliated Hospital of Chongqing College of Traditional Chinese Medicine, No. 40 Daomenkou St., District Yuzhong, Chongqing, 400011, P.R. China.
Yujuan XiaoDepartment of Dermatology, The First Affiliated Hospital of Chongqing College of Traditional Chinese Medicine, No. 40 Daomenkou St., District Yuzhong, Chongqing, 400011, P.R. China. xiaoyujuandoctor@163.com.
Yi LiuDepartment of Dermatology, The First Affiliated Hospital of Chongqing College of Traditional Chinese Medicine, No. 40 Daomenkou St., District Yuzhong, Chongqing, 400011, P.R. China. liuyifuzi@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes Simplex Virus-1 (HSV-1) Kaposi varicelliform eruption (KVE) is a rare and severe cutaneous manifestation, clinically characterized by the presence of widespread vesicles and pustules. A case report details a patient with a history of Atopic Dermatitis (AD) and recent SARS-CoV-2 infection who developed a severe KVE subsequent to the viral illness. The patient, a 35-year-old male, presented with severe atopic dermatitis (AD) subsequent to a SARS-CoV-2 infection. In a period of four months, the dermatological eruption underwent a rapid progression to a severe state, characterised by the presence of extensive vesicles and pustules, in addition to the emergence of symptoms. In conjunction with a chest CT scan, plasma and antigen testing, the patient was confirmed to be positive for HSV-1 positive. The patient exhibited elevated levels of IgE and a notable reduction in the absolute number of immune cells. The patient was treated with valaciclovir, piperacillin-tazobactam, IVIG at the same time. Within seven days of treatment, the blisters had dried up and the scabs had fallen off without any pain, pruritus, or fever. This case highlights the potential for severe viral eruptions, such as KVE in individuals with underlying dermatological conditions following viral infections.

Indexed as

Antibodies, Monoclonal, HumanizedCOVID-19Dermatitis, AtopicHerpesvirus 1, HumanKaposi Varicelliform EruptionSARS-CoV-2AdultAntiviral AgentsHerpes SimplexHumansMaleAntibodies, Monoclonal, HumanizedAntiviral AgentsdupilumabAtopic dermatitisDiagnosisHSV-1Kaposi varicelliform eruptionSARS-CoV-29Treatment

Identifiers

PMID39511481
PMCPMC11546167

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.