Evidence map›Paper›PMID 39511241›Full record

ArticleScientific reports2024

Performance and safety evaluation of a cold ablation robot-guided laser osteotome (CARLO) in 28 midface osteotomies.

Robert Köhnke, Shih-Jan Chin, Alexandre T Assaf, Katja Helmbold, Andreas A Müller, Philipp Juergens, Tobias Wilken, Sibylle Hirsch, Marta M Morawska, Jan Wolff and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. [Current applications and future perspectives of automation technologies and devices in oral diagnosis and treatment].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Robert KöhnkeDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany. r.koehnke@uke.de.
Shih-Jan ChinDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Alexandre T AssafDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Katja HelmboldDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Andreas A MüllerDepartment of Cranio-Maxillofacial Surgery, University Hospital, Basel, Switzerland.
Philipp JuergensDepartment of Cranio-Maxillofacial Surgery, University Hospital, Basel, Switzerland.
Tobias WilkenAdvanced Osteotomy Tools AG, Basel, Switzerland.
Sibylle HirschAdvanced Osteotomy Tools AG, Basel, Switzerland.
Marta M MorawskaAdvanced Osteotomy Tools AG, Basel, Switzerland.
Jan WolffDepartment of Dentistry and Oral Health - Section for Maxillofacial Surgery and Oral Pathology, Aarhus University, 8000, Aarhus C, Denmark.
Ralf SmeetsDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Lan KluweDepartment of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Daniel HolzingerDepartment of Oral and Maxillofacial Surgery, Medical University of Vienna, Vienna, Austria.
Kurt SchichoDepartment of Oral and Maxillofacial Surgery, Medical University of Vienna, Vienna, Austria.
Gabriele MillesiDepartment of Oral and Maxillofacial Surgery, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CARLO (cold ablation robot-guided laser osteotome) is a compact device with integrated multiple sensory, steering and safety checking elements. A multi-center study was performed to evaluate the CARLO device for the linear part of midface osteotomy in 28 patients. Feasibility, success rate, safety, performance and experience of the surgeons were assessed and evaluated. All 28 procedures were completed with CARLO without falling back to the conventional methods, giving a technical success rate of 100%. For 27 (96%) cases, procedural success was achieved with cutting lines deviation less than 2 mm. For 25 procedures, the CARLO-cutting was conducted smoothly. In the other 3 cases, some minor difficulties related to the reference markers were reported. For 18 procedures, no change for the cutting path was necessary. For the other 10 cases, cut path was adapted. Intraoperative re-planning was possible, easy and quick without significant delay of the procedures. No CARLO-related adverse events were recorded. Especially, there was no unexpected and unusual bleeding during the CARLO-conducted osteotomy. The time needed for the registration ranged from 1 to 12 min (median = 4). The CARLO-cutting lasted for 5 to 21 min (median = 7). The present study demonstrated feasibility, simplicity, safety, reliability and accuracy of CARLO for the linear part of midface osteotomy.

Indexed as

OsteotomyRobotic Surgical ProceduresAdolescentAdultFeasibility StudiesFemaleHumansLaser TherapyMaleMiddle AgedSurgery, Computer-AssistedYoung Adult3D-planningLaser guided osteotomyOrthognathic surgery

Identifiers

PMID39511241
PMCPMC11544146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.