Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Xiaochen LiuAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0001-6342-7704
David HikeAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0001-5294-1767
Sangcheon ChoiAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.
Weitao ManAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.
Chongzhao RanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.
Xiaoqing Alice ZhouAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0002-4139-032X
Yuanyuan JiangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0001-7758-7450
Xin YuAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA. XYU9@mgh.harvard.edu.ORCID 0000-0001-9890-5489
Funding
Project 4U19NS123717 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LINNINGER, ANDREAS A · 2021 to 2025
$13.4M
Investigating the Thalamic Regulation of Neuro-Glio-Vascular Restoration Underlying Acute Coma Recovery with Multi-Modal fMRI in a Brainstem Coma Rodent ModelR01NS122904 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI YU, XIN · 2021 to 2025
$3.2M
Simultaneous functional MRI and Micro-Magnetic Nervous System StimulationR01NS120594 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AY, ILKNUR, BONMASSAR, GIORGIO · 2021 to 2021
$2.2M
Investigating the neurophysiological basis of circuit-specific laminar rs-fMRIRF1NS124778 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BISWAL, BHARAT BHUSAN, BROWN, EMERY N · 2022 to 2022
$2.1M
Develop a multi-modal cross-scale fMRI platform with laminar-specific cellular recordings through multi-channel tapered photonic crystal fiber arrayRF1NS113278 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI YU, XIN · 2019 to 2019
$2.0M
Upgrade of the Preclinical Horizontal 14T MagnetS10OD036211 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI YU, XIN · 2024 to 2024
$2.0M
Bridging the cellular and microvascular anatomy and functional dynamics: Upgrade the 14T horizontal MR for rodent and ex-vivo imagingS10MH124733 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R, YU, XIN · 2020 to 2020
$600k
Upgrade the 14T Ultrahigh Field Horizontal MR Scanner for Rodent and ex-vivo ImagingS10OD028616 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2021 to 2021
$600k
Development of a Multi-Modal MRI Methodology to Map Paravascular Clearance Linked to Astrocyte Dysfunction in Fetal-Onset HydrocephalusR21NS121642 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI YU, XIN · 2021 to 2021
$462k
National Science Foundation (NSF) 2123970NIH HHS S10 OD028616NIH HHS S10 OD036211NIMH NIH HHS S10 MH124733NINDS NIH HHS R01 NS120594NINDS NIH HHS R01 NS122904NINDS NIH HHS R21 NS121642NINDS NIH HHS RF1 NS113278NINDS NIH HHS RF1 NS124778NINDS NIH HHS U19 NS123717U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) RF1NS113278, RF1NS124778, R01NS122904, R01NS120594, and R21NS121642
6 · The paper itself
Abstract
Pupil dynamics has emerged as a critical non-invasive indicator of brain state changes. In particular, pupillary-light-responses (PLR) in Alzheimer's disease (AD) patients show potential as biomarkers for brain degeneration. To investigate AD-specific PLR and its underlying neuromodulatory sources, we combine high-resolution awake mouse fMRI with real-time pupillometry to map brain-wide event-related correlation patterns based on illumination-driven pupil constriction (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Identifying the bioimaging features of Alzheimer's disease based on pupillary light response-driven brain-wide fMRI in awake mice. · full record | OpenQuestion