Evidence map›Paper›PMID 39511036›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2024

Evaluating the Correlation Between Stimulus Frequency Otoacoustic Emission Group Delays and Tuning Sharpness in a Cochlear Model.

Yiwei Xia, George Samaras, Julien Meaud

Abstract read
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yiwei Xia *George W. Woodruff School of Mechanical Engineering Atlanta, GA, Atlanta, 30332, USA.
George Samaras *George W. Woodruff School of Mechanical Engineering Atlanta, GA, Atlanta, 30332, USA.
Julien MeaudGeorge W. Woodruff School of Mechanical Engineering Atlanta, GA, Atlanta, 30332, USA. julien.meaud@me.gatech.edu.ORCID http://orcid.org/0000-0002-8039-0138

Funding

Modeling cochlear micromechanics and noninvasive measures of cochlear functionR01DC016114 · NIDCD · GEORGIA INSTITUTE OF TECHNOLOGY · PI Julien Meaud · 2018 to 2026
$2.1M
NIDCD NIH HHS R01 DC016114
6 · The paper itself

Abstract

purposeA theoretical framework based on coherent reflection and filter theory predicts that the phase-gradient delays of stimulus frequency otoacoustic emissions (SFOAEs) are correlated with tuning sharpness in the mammalian cochlea. In this paper, we use a computational model of the cochlea to test this theory and to evaluate how SFOAE phase-gradient delays may be used to estimate the sharpness of cochlear tuning.

methodsThis study is based on a physiologically motivated model which has been previously shown to predict key aspects of cochlear micromechanics. Cochlear roughness is introduced to model the reflection mechanism which underlies SFOAE generation. We then examine how varying the values of key model parameters or of the sound pressure level of the stimulus affects the relation between cochlear tuning and SFOAE delays. Finally, we quantify the ability of model simulations of SFOAE phase-gradient delays to provide reliable estimates of the tuning sharpness of the model.

resultsWe find that variations of model parameters that cause significant broadening of basilar membrane (BM) tuning typically give rise to a sizeable reduction in SFOAE phase-gradient delays. However, some changes in model parameters may cause a significant broadening of BM tuning with only a moderate decrease in SFOAE delays. SFOAE delays can be used to estimate the tuning sharpness of the model with reasonable accuracy only in cases where broadening of cochlear tuning is associated with a significant reduction in SFOAE delays.

conclusionThe numerical results provide key insights about the correlations between cochlear tuning and SFOAE delays.

Indexed as

CochleaModels, BiologicalOtoacoustic Emissions, SpontaneousAcoustic StimulationAnimalsHumansCochlear modelCochlear tuningGroup delayOtoacoustic emissions

Identifiers

PMID39511036
PMCPMC11683045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.