Evidence map›Paper›PMID 39511014›Full record

ArticleAnalytical and bioanalytical chemistry2025

Reversible addition-fragmentation chain transfer enhanced aggregation signal-on fluorescence detection of alkaline phosphatase.

Shuaibing Yu, Lianzhi Li, Qiyun Kong, Wenqi Zhang, Huan Chen, Xueji Zhang, Jinming Kong

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuaibing YuCollege of the Environment & Ecology, Jiangsu Open University, Nanjing, 210017, PR China.
Lianzhi LiSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, 252059, PR China.
Qiyun KongHwa Chong Institution, 661 Bukit Timah Road, Singapore, 269734, Singapore.
Wenqi ZhangCollege of the Environment & Ecology, Jiangsu Open University, Nanjing, 210017, PR China.
Huan ChenSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China.
Xueji ZhangSchool of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, PR China.
Jinming KongSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China. j.kong@njust.edu.cn.

Funding

2023 Jiangsu Provincial Collaboration Between Industry, Academia and Research Institutions Project BY20230536National Natural Science Foundation of China 21974068
6 · The paper itself

Abstract

The instability of the signal intensity of fluorescent biosensors and the false signals have been significant factors affecting the performance of biosensors. Herein, a novel signaling system is devised through the application of reversible addition-fragmentation chain transfer (RAFT) polymerization with monomers containing the tetraphenylethylene (TPE) groups. TPE exhibits an aggregation-induced emission (AIE) phenomenon in certain solvents, mainly due to the blockage of the rotation of its four benzene rings, which also exist in the aggregated state. With this property, a series of molecules are modified based on click chemistry for RAFT polymerization using Fe

Indexed as

Alkaline PhosphataseBiosensing TechniquesLimit of DetectionSpectrometry, FluorescenceStilbenesFluorescenceFluorescent DyesHumansPolymerizationPolymersAlkaline PhosphataseFluorescent DyesPolymersStilbenestetraphenylethyleneAggregation-induced emissionALPControlled chain growth luminescenceFluorescent biosensorRAFT polymerization

Identifiers

PMID39511014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.