Evidence map›Paper›PMID 39510806›Full record

ArticleAJNR. American journal of neuroradiology2024

Dural Arteriovenous Fistulas: Baseline Cognitive Changes and Changes following Treatment: A Prospective Longitudinal Study.

Zeev Itsekson-Hayosh, Federico Carpani, Pascal J Mosimann, Ronit Agid, Eef J Hendriks, Ivan Radovanovic, Hugo Andrade Barazarte, Joanna D Schaafsma, Karel Terbrugge, Timo Krings and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Glymphatic System and Its Role in Neurovascular Diseases.Journal of neuroendovascular therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zeev Itsekson-HayoshFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada zeevits@gmail.com.ORCID 0000-0001-8320-4129
Federico CarpaniDepartment of Neurology, (F.C., J.D.S.), Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Pascal J MosimannFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Ronit AgidFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-4686-1685
Eef J HendriksFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-2100-7992
Ivan RadovanovicDepartment of Neurosurgery (P.J.M., E.J.H., I.R., H.A.B., T.K), Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Hugo Andrade BarazarteDepartment of Neurosurgery (P.J.M., E.J.H., I.R., H.A.B., T.K), Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Joanna D SchaafsmaDepartment of Neurology, (F.C., J.D.S.), Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-4326-5597
Karel TerbruggeFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.
Timo KringsFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-6321-5787
Mary Pat McAndrewsDepartment of Psychology (M.P.M.), University of Toronto, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Patrick NicholsonFrom the Division of Neuroradiology (Z.I.-H., P.J.M., R.A., E.J.H., K.T., T.K., P.N.), University Medical Imaging and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-7182-5112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDural arteriovenous fistulas (DAVFs) exhibit varied clinical manifestations, and high-grade cases are associated with both a risk of hemorrhage and (in certain cases) dementia. Less known, however, is the association between DAVF and more subtle cognitive changes, which might not be clinically apparent without formal neurocognitive testing. This study prospectively assesses baseline cognitive changes in patients with unruptured DAVFs and looks at the effects of treatment on any such changes. MATERIALS AND

methodsA longitudinal prospective study was conducted to formally evaluate the neurocognitive status of patients with unruptured DAVFs undergoing embolization. Pre- and posttreatment assessments included neurologic examinations and cognitive tests (Repeatable Battery for the Assessment of Neuropsychological Status and Trail-Making Test [TMT]).

resultsA total of 23 patients were treated, with 78% demonstrating cortical venous reflux at baseline. At baseline, 50% of patients demonstrated cognitive impairment in at least 1 cognitive domain, and this was significantly associated with cortical venous reflux (

conclusionsIn our study, 50% of patients with DAVFs had cognitive impairment when assessed with formal neurocognitive testing, with a significant link to cortical venous reflux. This cognitive impairment improved in 70% of those patients following treatment. These findings expand our understanding of how DAVF affects the brain, highlighting cognitive impairment as a critical factor. Consequently, the treatment of DAVFs should perhaps not only focus on hemorrhagic risk but also consider cognitive outcomes as a potential indicator for intervention.

Indexed as

Central Nervous System Vascular MalformationsEmbolization, TherapeuticAdultAgedCognitive DysfunctionFemaleHumansLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsProspective StudiesTreatment Outcome

Identifiers

PMID39510806
PMCPMC11630883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.